Actively Recruiting
Adaptive Randomization of Aerobic Exercise During Chemotherapy in Colon Cancer
Led by AdventHealth Translational Research Institute · Updated on 2026-01-07
219
Participants Needed
3
Research Sites
204 weeks
Total Duration
On this page
Sponsors
A
AdventHealth Translational Research Institute
Lead Sponsor
N
National Cancer Institute (NCI)
Collaborating Sponsor
AI-Summary
What this Trial Is About
To goal of this clinical trial is to quantify the dose-response effects of aerobic exercise training compared to attention control on chemotherapy relative dose intensity in colon cancer survivors.
CONDITIONS
Official Title
Adaptive Randomization of Aerobic Exercise During Chemotherapy in Colon Cancer
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age 6518 years
- Histologically confirmed stage II or III colon cancer
- Completed surgical resection with curative intent
- Planned initiation of chemotherapy
- Engages in less than 60 minutes per week of moderate- to vigorous-intensity structured aerobic exercise
- No planned major surgery during the study period
- Ready to exercise as determined by a modified Physical Activity Readiness Questionnaire
- Able to walk 400 meters
- Able to read and speak English
- Able to provide written informed consent
- Written approval from a qualified healthcare professional
- Willingness to be randomized
You will not qualify if you...
- Evidence of metastatic colon cancer
- Currently receiving active treatment for another cancer (not colon cancer)
- Currently pregnant, breastfeeding, or planning pregnancy within 24 weeks
- Participating in another study with competing outcomes
- Any condition that investigator believes prevents participation or compliance
- Any situation that investigator believes could impact safety or compliance
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 3 locations
1
Kaiser Permanente Northern California
Oakland, California, United States, 94612
Actively Recruiting
2
AdventHealth
Orlando, Florida, United States, 32804
Actively Recruiting
3
Dana-Farber Cancer Institute
Boston, Massachusetts, United States, 02215
Actively Recruiting
Research Team
J
Justin C. Brown, Ph.D.
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
DOUBLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
SUPPORTIVE_CARE
Number of Arms
5
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here