Actively Recruiting
Adaptive Stereotactic Radiotherapy for Localized Prostate Cancer
Led by Clinique Sainte Clotilde · Updated on 2026-01-15
100
Participants Needed
1
Research Sites
180 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This study evaluates whether adaptive stereotactic body radiotherapy (SBRT) provides dosimetric advantages compared to non-adaptive SBRT in localized prostate cancer. Five low-dose CT scans are performed before each SBRT session to assess anatomical variations (bladder filling, rectal volume) and determine if a dosimetric recalculation would have been required. The study also evaluates cumulative dose to organs at risk, patient-reported quality of life over 24 months, and overall and recurrence-free survival.
CONDITIONS
Official Title
Adaptive Stereotactic Radiotherapy for Localized Prostate Cancer
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Male aged 60 years or older
- Diagnosed with localized prostate cancer of low or intermediate risk (T1-T2)
- Gleason score between 6 and 7
- PSA level less than 15 ng/mL
- No evidence of metastatic disease
- Radiotherapy is indicated for prostate cancer treatment
- Affiliated with or benefiting from the French social security system
- Patient speaks French
- Patient has been informed and has signed a written informed consent form
You will not qualify if you...
- Unable to read, write, or understand French
- Considered a vulnerable patient as defined by French Public Health Code Article L1121-6
- Under guardianship, curatorship, or legal protection ("sauvegarde de justice")
- Unable to provide informed consent personally according to French Public Health Code Article L1121-8
- Already participating in another interventional study that could affect outcomes
- History of urological (prostate) or digestive surgery that may influence study results
- Refusal to sign the written informed consent form
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
Clinique Sainte Clotilde
Saint-Denis, Reunion, 97404
Actively Recruiting
Research Team
M
MANON Leprince, Clinical Research Associate
CONTACT
M
Mickael Begue, Principal Investigator
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
DIAGNOSTIC
Number of Arms
1
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