Actively Recruiting

Age: 18Years +
MALE
NCT06737588

The Addictive Diagnostic Value of Apparent Diffusion Coefficients to bpMRI in the Diagnosis of Prostate Cancer

Led by Anhui Provincial Hospital · Updated on 2025-02-11

600

Participants Needed

2

Research Sites

121 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The goal of this study is to evaluate the diagnostic value of different ADC values (incuding ADCmin, ADCmean, ADCratio and ADCrange) of bpMRI in patients with PI-RADS 3-5. The main aim is to evaluate whether different ADC values improve the diagnosis of clinically significant prostate cancer (Gleasonscore≥3+4, ISUP grade ≥2) and any-grade prostate cancer (Gleasonscore≥3+3, ISUP grade ≥1).

CONDITIONS

Official Title

The Addictive Diagnostic Value of Apparent Diffusion Coefficients to bpMRI in the Diagnosis of Prostate Cancer

Who Can Participate

Age: 18Years +
MALE

Eligibility Criteria

Eligible

You may qualify if you...

  • Patient meets at least one indication for prostate biopsy according to the Chinese expert consensus on prostate biopsy (2022 edition)
  • Serum PSA test completed with total PSA less than 100 ng/ml
  • Primary prostate tumor lesion present with no history of other tumors
  • Completed 3.0T biparametric MRI with PI-RADS score of 3 or higher; images are clear and readable
  • Patients fully understand study details and voluntarily sign informed consent
Not Eligible

You will not qualify if you...

  • Contraindications for MRI present
  • PI-RADS score of 1 or 2 on biparametric MRI
  • Contraindications to prostate biopsy or explicit refusal of biopsy
  • Biparametric MRI shows multiple lymph nodes or bone metastases
  • Previous prostate-related surgery
  • Patient refuses to sign informed consent

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 2 locations

1

Department of Urology, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China

Hefei, Anhui, China, 230001

Actively Recruiting

2

Department of Urology, The First Affiliated Hospital of Wannan Medical College

Wuhu, Anhui, China, 241000

Not Yet Recruiting

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Research Team

C

Changming Wang

CONTACT

J

Jun Xiao

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

0

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The Addictive Diagnostic Value of Apparent Diffusion Coefficients to bpMRI in the Diagnosis of Prostate Cancer | DecenTrialz