Actively Recruiting
Adding Amantadine or Duloxetine to Pregabalin on Occurrence of Post Mastectomy Pain Syndrome
Led by Cairo University · Updated on 2026-02-24
150
Participants Needed
1
Research Sites
44 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This study aims to evaluate the additive effect of Amantadine or Duloxetine to Pregabalin on development of post mastectomy pain syndrome
CONDITIONS
Official Title
Adding Amantadine or Duloxetine to Pregabalin on Occurrence of Post Mastectomy Pain Syndrome
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age from 18 to 65 years
- American Society of Anesthesiologists (ASA) physical status II or III
- Body mass index (BMI) between 20 and 40 kg/m2
- Undergoing modified radical mastectomy for breast cancer
You will not qualify if you...
- Patient refusal to participate
- Known sensitivity or contraindication to study drugs
- History of psychological disorders, chronic pain, or drug abuse
- Use of antidepressants, anticonvulsants, or opioids before surgery
- Severe respiratory or cardiac problems
- Advanced liver or kidney disease
- Previous breast surgery
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
Cairo University
Cairo, Egypt, 12613
Actively Recruiting
Research Team
H
Hossam H Sayed, MSc
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
DOUBLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
3
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