Actively Recruiting
Adding Nivolumab to Usual Treatment for People With Advanced Stomach or Esophageal Cancer, PARAMUNE Trial
Led by National Cancer Institute (NCI) · Updated on 2026-05-14
224
Participants Needed
371
Research Sites
174 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This phase II/III trial compares the addition of nivolumab to the usual treatment of paclitaxel and ramucirumab to paclitaxel and ramucirumab alone in treating patients with gastric or esophageal adenocarcinoma that may have spread from where it first started to nearby tissue, lymph nodes, or distant parts of the body (advanced). A monoclonal antibody is a type of protein that can bind to certain targets in the body, such as molecules that cause the body to make an immune response (antigens). Immunotherapy with monoclonal antibodies, such as nivolumab, may help the body's immune system attack the cancer, and may interfere with the ability of tumor cells to grow and spread. Ramucirumab is a monoclonal antibody that may prevent the growth of new blood vessels that tumors need to grow. Paclitaxel is in a class of medications called antimicrotubule agents. It stops cancer cells from growing and dividing and may kill them. Adding nivolumab to ramucirumab and paclitaxel may work better to treat patients with advanced stomach or esophageal cancer.
CONDITIONS
Official Title
Adding Nivolumab to Usual Treatment for People With Advanced Stomach or Esophageal Cancer, PARAMUNE Trial
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Participants must have advanced or locally unresectable gastric, gastroesophageal junction, or esophageal adenocarcinoma
- Participants must have PD-L1 CPS (Combined Positive Score) 21 1 from testing within two years prior to registration
- Histologically confirmed microsatellite stable (MSS) and HER2 negative gastric, gastroesophageal junction, or esophageal adenocarcinoma
- Documented unresectable and/or metastatic disease on CT or MRI imaging completed within 28 days for measurable disease or 42 days for non-measurable disease prior to registration
- Participants with treated brain metastases must have no progression on follow-up imaging after CNS-directed therapy completed at least 28 days prior
- Disease progression or intolerance to frontline chemotherapy plus PD-1 or PD-L1 inhibitor
- No more than one prior line of systemic therapy including chemotherapy plus PD-1 or PD-L1 inhibitor in stage IV or unresectable setting
- No systemic corticosteroids over 10 mg prednisone equivalents or immunosuppressive medications within 14 days prior to registration, except certain topical or physiologic doses
- No prior significant immunotherapy adverse events requiring permanent discontinuation
- No live attenuated vaccination within 28 days prior to registration
- No major surgery within 28 days or subcutaneous venous device placement within 7 days prior to registration
- Fully recovered from prior surgery effects without bleeding or wound complications
- No plans for elective or planned major surgery during the study
- No active bleeding or significant gastrointestinal bleeding, perforation, or fistula within 84 days prior to registration
- No concurrent chemotherapy, immunotherapy, investigational agents, biologics, or hormonal therapy during study treatment
- No history of grade 3 or 4 allergic reaction to monoclonal antibody therapy
- Participants must be 18 years or older
- Zubrod Performance Status 0-2
- Complete medical history and physical exam within 28 days prior to registration
- Adequate blood counts and organ function within 28 days prior to registration
- Adequate cardiac function with NYHA class 2 or better
- Recovery to baseline or less than grade 2 toxicity from prior treatments
- No arterial thromboembolic events within 6 months prior to registration
- Controlled blood pressure within 28 days prior to registration
- Effective control of HIV, HBV, or HCV infection if present
- No prior or concurrent malignancy that may interfere with study assessment
- Not pregnant or nursing and agreeing to use effective contraception if of reproductive potential
- No history of inflammatory bowel disease or symptomatic autoimmune disease except Graves' disease
- No pneumonitis requiring steroids within 12 months prior to registration
- Willingness to participate in specimen banking and quality of life questionnaires
- Ability to provide informed consent or have a legally authorized representative consent
You will not qualify if you...
- History of significant immunotherapy adverse events requiring permanent discontinuation such as pneumonitis, myocarditis, renal failure, Guillain-Barre syndrome, or myasthenia gravis
- Receipt of live attenuated vaccination within 28 days prior to registration
- Major surgery within 28 days or subcutaneous venous access device placement within 7 days prior to registration
- Active bleeding or history of gastrointestinal perforation, fistula, or significant bleeding within 84 days prior to registration
- Concurrent treatment with other chemotherapy, immunotherapy, investigational agents, biologic or hormonal therapy for cancer
- History of grade 3 or 4 allergic reaction to humanized or human monoclonal antibody therapy
- History of grade 3 or 4 immunotherapy-related toxicities except for hormonal abnormalities
- Plans for elective or planned major surgery during the trial
- History of inflammatory bowel disease or symptomatic autoimmune diseases except Graves' disease
- Pneumonitis requiring oral or IV steroids within 12 months prior to registration
- Arterial thromboembolic events within 6 months prior to registration
- Uncontrolled blood pressure within 28 days prior to registration
- Prior or concurrent malignancy interfering with safety or efficacy assessments
- Pregnancy or nursing status
- Inability to provide informed consent or lack of legally authorized representative consent if needed
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 371 locations
1
Baptist Health Medical Center - Little Rock
Little Rock, Arkansas, United States, 72205
Actively Recruiting
2
University of Arkansas for Medical Sciences
Little Rock, Arkansas, United States, 72205
Actively Recruiting
3
Kaiser Permanente-Anaheim
Anaheim, California, United States, 92806
Actively Recruiting
4
Kaiser Permanente-Baldwin Park
Baldwin Park, California, United States, 91706
Actively Recruiting
5
Kaiser Permanente-Bellflower
Bellflower, California, United States, 90706
Actively Recruiting
6
Tower Cancer Research Foundation
Beverly Hills, California, United States, 90211
Actively Recruiting
7
Kaiser Permanente Dublin
Dublin, California, United States, 94568
Actively Recruiting
8
Kaiser Permanente-Fontana
Fontana, California, United States, 92335
Actively Recruiting
9
Kaiser Permanente-Fremont
Fremont, California, United States, 94538
Actively Recruiting
10
Kaiser Permanente Fresno Orchard Plaza
Fresno, California, United States, 93720
Actively Recruiting
11
Kaiser Permanente-Fresno
Fresno, California, United States, 93720
Actively Recruiting
12
Kaiser Permanente South Bay
Harbor City, California, United States, 90710
Actively Recruiting
13
Kaiser Permanente-Irvine
Irvine, California, United States, 92618
Actively Recruiting
14
UC San Diego Moores Cancer Center
La Jolla, California, United States, 92093
Actively Recruiting
15
Keck Medicine of USC Koreatown
Los Angeles, California, United States, 90020
Actively Recruiting
16
Kaiser Permanente Los Angeles Medical Center
Los Angeles, California, United States, 90027
Actively Recruiting
17
Los Angeles General Medical Center
Los Angeles, California, United States, 90033
Actively Recruiting
18
USC / Norris Comprehensive Cancer Center
Los Angeles, California, United States, 90033
Actively Recruiting
19
Kaiser Permanente West Los Angeles
Los Angeles, California, United States, 90034
Actively Recruiting
20
Cedars-Sinai Medical Center
Los Angeles, California, United States, 90048
Actively Recruiting
21
Kaiser Permanente- Modesto MOB II
Modesto, California, United States, 95356
Actively Recruiting
22
Kaiser Permanente-Modesto
Modesto, California, United States, 95356
Actively Recruiting
23
USC Norris Oncology/Hematology-Newport Beach
Newport Beach, California, United States, 92663
Actively Recruiting
24
Kaiser Permanente-Oakland
Oakland, California, United States, 94611
Actively Recruiting
25
Kaiser Permanente-Ontario
Ontario, California, United States, 91761
Actively Recruiting
26
Kaiser Permanente - Panorama City
Panorama City, California, United States, 91402
Actively Recruiting
27
Kaiser Permanente-Riverside
Riverside, California, United States, 92505
Actively Recruiting
28
Kaiser Permanente-Roseville
Roseville, California, United States, 95661
Actively Recruiting
29
Kaiser Permanente Downtown Commons
Sacramento, California, United States, 95814
Actively Recruiting
30
University of California Davis Comprehensive Cancer Center
Sacramento, California, United States, 95817
Actively Recruiting
31
Kaiser Permanente-South Sacramento
Sacramento, California, United States, 95823
Actively Recruiting
32
Kaiser Permanente-San Diego Zion
San Diego, California, United States, 92120
Actively Recruiting
33
Kaiser Permanente-San Francisco
San Francisco, California, United States, 94115
Actively Recruiting
34
Kaiser Permanente-Santa Teresa-San Jose
San Jose, California, United States, 95119
Actively Recruiting
35
Kaiser Permanente San Leandro
San Leandro, California, United States, 94577
Actively Recruiting
36
Kaiser Permanente-San Marcos
San Marcos, California, United States, 92078
Actively Recruiting
37
Kaiser San Rafael-Gallinas
San Rafael, California, United States, 94903
Actively Recruiting
38
Kaiser Permanente Medical Center - Santa Clara
Santa Clara, California, United States, 95051
Actively Recruiting
39
Kaiser Permanente-Santa Rosa
Santa Rosa, California, United States, 95403
Actively Recruiting
40
Kaiser Permanente-South San Francisco
South San Francisco, California, United States, 94080
Actively Recruiting
41
Kaiser Permanente-Vallejo
Vallejo, California, United States, 94589
Actively Recruiting
42
Kaiser Permanente-Walnut Creek
Walnut Creek, California, United States, 94596
Actively Recruiting
43
Kaiser Permanente-Woodland Hills
Woodland Hills, California, United States, 91367
Actively Recruiting
44
UCHealth Memorial Hospital Central
Colorado Springs, Colorado, United States, 80909
Actively Recruiting
45
Memorial Hospital North
Colorado Springs, Colorado, United States, 80920
Actively Recruiting
46
Poudre Valley Hospital
Fort Collins, Colorado, United States, 80524
Actively Recruiting
47
Cancer Care and Hematology-Fort Collins
Fort Collins, Colorado, United States, 80528
Actively Recruiting
48
UCHealth Greeley Hospital
Greeley, Colorado, United States, 80631
Actively Recruiting
49
Medical Center of the Rockies
Loveland, Colorado, United States, 80538
Actively Recruiting
50
Smilow Cancer Hospital-Derby Care Center
Derby, Connecticut, United States, 06418
Actively Recruiting
51
Smilow Cancer Hospital Care Center-Fairfield
Fairfield, Connecticut, United States, 06824
Actively Recruiting
52
Smilow Cancer Hospital Care Center at Glastonbury
Glastonbury, Connecticut, United States, 06033
Actively Recruiting
53
Smilow Cancer Hospital Care Center at Greenwich
Greenwich, Connecticut, United States, 06830
Actively Recruiting
54
Smilow Cancer Hospital Care Center - Guilford
Guilford, Connecticut, United States, 06437
Actively Recruiting
55
Smilow Cancer Hospital Care Center at Saint Francis
Hartford, Connecticut, United States, 06105
Actively Recruiting
56
Yale University
New Haven, Connecticut, United States, 06520
Actively Recruiting
57
Yale-New Haven Hospital North Haven Medical Center
North Haven, Connecticut, United States, 06473
Actively Recruiting
58
Smilow Cancer Hospital Care Center at Long Ridge
Stamford, Connecticut, United States, 06902
Actively Recruiting
59
Smilow Cancer Hospital-Torrington Care Center
Torrington, Connecticut, United States, 06790
Actively Recruiting
60
Smilow Cancer Hospital Care Center-Trumbull
Trumbull, Connecticut, United States, 06611
Actively Recruiting
61
Smilow Cancer Hospital-Waterbury Care Center
Waterbury, Connecticut, United States, 06708
Actively Recruiting
62
Smilow Cancer Hospital Care Center - Waterford
Waterford, Connecticut, United States, 06385
Actively Recruiting
63
Beebe South Coastal Health Campus
Millville, Delaware, United States, 19967
Actively Recruiting
64
Helen F Graham Cancer Center
Newark, Delaware, United States, 19713
Actively Recruiting
65
Medical Oncology Hematology Consultants PA
Newark, Delaware, United States, 19713
Actively Recruiting
66
Beebe Health Campus
Rehoboth Beach, Delaware, United States, 19971
Actively Recruiting
67
MedStar Georgetown University Hospital
Washington D.C., District of Columbia, United States, 20007
Actively Recruiting
68
AdventHealth Orlando
Orlando, Florida, United States, 32803
Actively Recruiting
69
Emory University Hospital Midtown
Atlanta, Georgia, United States, 30308
Actively Recruiting
70
Emory University Hospital/Winship Cancer Institute
Atlanta, Georgia, United States, 30322
Actively Recruiting
71
Emory Saint Joseph's Hospital
Atlanta, Georgia, United States, 30342
Actively Recruiting
72
Emory Decatur Hospital
Decatur, Georgia, United States, 30033
Actively Recruiting
73
Emory Johns Creek Hospital
Johns Creek, Georgia, United States, 30097
Actively Recruiting
74
Hawaii Cancer Care Inc - Waterfront Plaza
Honolulu, Hawaii, United States, 96813
Actively Recruiting
75
Queen's Cancer Cenrer - POB I
Honolulu, Hawaii, United States, 96813
Actively Recruiting
76
Queen's Medical Center
Honolulu, Hawaii, United States, 96813
Actively Recruiting
77
Straub Clinic and Hospital
Honolulu, Hawaii, United States, 96813
Actively Recruiting
78
Queen's Cancer Center - Kuakini
Honolulu, Hawaii, United States, 96817
Actively Recruiting
79
Kaiser Permanente Moanalua Medical Center
Honolulu, Hawaii, United States, 96819
Actively Recruiting
80
Kapiolani Medical Center for Women and Children
Honolulu, Hawaii, United States, 96826
Actively Recruiting
81
Hawaii Cancer Care - Westridge
‘Aiea, Hawaii, United States, 96701
Actively Recruiting
82
Pali Momi Medical Center
‘Aiea, Hawaii, United States, 96701
Actively Recruiting
83
The Queen's Medical Center - West Oahu
‘Ewa Beach, Hawaii, United States, 96706
Actively Recruiting
84
Saint Alphonsus Cancer Care Center-Boise
Boise, Idaho, United States, 83706
Actively Recruiting
85
Saint Alphonsus Cancer Care Center-Caldwell
Caldwell, Idaho, United States, 83605
Actively Recruiting
86
Kootenai Health - Coeur d'Alene
Coeur d'Alene, Idaho, United States, 83814
Actively Recruiting
87
Saint Alphonsus Cancer Care Center-Nampa
Nampa, Idaho, United States, 83687
Actively Recruiting
88
Kootenai Clinic Cancer Services - Post Falls
Post Falls, Idaho, United States, 83854
Actively Recruiting
89
Kootenai Clinic Cancer Services - Sandpoint
Sandpoint, Idaho, United States, 83864
Actively Recruiting
90
Rush-Copley Medical Center
Aurora, Illinois, United States, 60504
Actively Recruiting
91
Advocate Outpatient Center - Aurora
Aurora, Illinois, United States, 60506
Actively Recruiting
92
Advocate Good Shepherd Hospital
Barrington, Illinois, United States, 60010
Actively Recruiting
93
Illinois CancerCare-Bloomington
Bloomington, Illinois, United States, 61704
Suspended
94
Illinois CancerCare-Canton
Canton, Illinois, United States, 61520
Suspended
95
Illinois CancerCare-Carthage
Carthage, Illinois, United States, 62321
Suspended
96
Northwestern University
Chicago, Illinois, United States, 60611
Actively Recruiting
97
University of Illinois
Chicago, Illinois, United States, 60612
Actively Recruiting
98
Swedish Covenant Hospital
Chicago, Illinois, United States, 60625
Actively Recruiting
99
University of Chicago Comprehensive Cancer Center
Chicago, Illinois, United States, 60637
Actively Recruiting
100
Advocate Illinois Masonic Medical Center
Chicago, Illinois, United States, 60657
Actively Recruiting
101
AMG Crystal Lake - Oncology
Crystal Lake, Illinois, United States, 60014
Actively Recruiting
102
Carle at The Riverfront
Danville, Illinois, United States, 61832
Actively Recruiting
103
Cancer Care Specialists of Illinois - Decatur
Decatur, Illinois, United States, 62526
Actively Recruiting
104
Decatur Memorial Hospital
Decatur, Illinois, United States, 62526
Actively Recruiting
105
Northwestern Medicine Cancer Center Kishwaukee
DeKalb, Illinois, United States, 60115
Actively Recruiting
106
Illinois CancerCare-Dixon
Dixon, Illinois, United States, 61021
Suspended
107
Advocate Good Samaritan Hospital
Downers Grove, Illinois, United States, 60515
Actively Recruiting
108
Carle Physician Group-Effingham
Effingham, Illinois, United States, 62401
Actively Recruiting
109
Crossroads Cancer Center
Effingham, Illinois, United States, 62401
Actively Recruiting
110
Advocate Sherman Hospital
Elgin, Illinois, United States, 60123
Actively Recruiting
111
Illinois CancerCare-Eureka
Eureka, Illinois, United States, 61530
Suspended
112
NorthShore University HealthSystem-Evanston Hospital
Evanston, Illinois, United States, 60201
Actively Recruiting
113
Illinois CancerCare-Galesburg
Galesburg, Illinois, United States, 61401
Suspended
114
Northwestern Medicine Cancer Center Delnor
Geneva, Illinois, United States, 60134
Actively Recruiting
115
NorthShore University HealthSystem-Glenbrook Hospital
Glenview, Illinois, United States, 60026
Actively Recruiting
116
Northwestern Medicine Glenview Outpatient Center
Glenview, Illinois, United States, 60026
Actively Recruiting
117
Northwestern Medicine Grayslake Outpatient Center
Grayslake, Illinois, United States, 60030
Actively Recruiting
118
Ingalls Memorial Hospital
Harvey, Illinois, United States, 60426
Actively Recruiting
119
Advocate South Suburban Hospital
Hazel Crest, Illinois, United States, 60429
Actively Recruiting
120
NorthShore University HealthSystem-Highland Park Hospital
Highland Park, Illinois, United States, 60035
Actively Recruiting
121
Illinois CancerCare-Kewanee Clinic
Kewanee, Illinois, United States, 61443
Suspended
122
Northwestern Medicine Lake Forest Hospital
Lake Forest, Illinois, United States, 60045
Actively Recruiting
123
AMG Libertyville - Oncology
Libertyville, Illinois, United States, 60048
Actively Recruiting
124
Condell Memorial Hospital
Libertyville, Illinois, United States, 60048
Actively Recruiting
125
Illinois CancerCare-Macomb
Macomb, Illinois, United States, 61455
Suspended
126
Carle Physician Group-Mattoon/Charleston
Mattoon, Illinois, United States, 61938
Actively Recruiting
127
UC Comprehensive Cancer Center at Silver Cross
New Lenox, Illinois, United States, 60451
Actively Recruiting
128
Cancer Care Center of O'Fallon
O'Fallon, Illinois, United States, 62269
Actively Recruiting
129
Northwestern Medicine Oak Brook
Oak Brook, Illinois, United States, 60523
Actively Recruiting
130
Advocate Christ Medical Center
Oak Lawn, Illinois, United States, 60453-2699
Actively Recruiting
131
Northwestern Medicine Orland Park
Orland Park, Illinois, United States, 60462
Actively Recruiting
132
University of Chicago Medicine-Orland Park
Orland Park, Illinois, United States, 60462
Actively Recruiting
133
Illinois CancerCare-Ottawa Clinic
Ottawa, Illinois, United States, 61350
Suspended
134
Advocate Lutheran General Hospital
Park Ridge, Illinois, United States, 60068
Actively Recruiting
135
Illinois CancerCare-Pekin
Pekin, Illinois, United States, 61554
Suspended
136
Illinois CancerCare-Peoria
Peoria, Illinois, United States, 61615
Suspended
137
Illinois CancerCare-Peru
Peru, Illinois, United States, 61354
Suspended
138
Illinois CancerCare-Princeton
Princeton, Illinois, United States, 61356
Suspended
139
Mercyhealth Cancer Institute - Rockford
Rockford, Illinois, United States, 61114
Actively Recruiting
140
UW Health Carbone Cancer Center Rockford
Rockford, Illinois, United States, 61114
Actively Recruiting
141
Memorial Hospital East
Shiloh, Illinois, United States, 62269
Actively Recruiting
142
Southern Illinois University School of Medicine
Springfield, Illinois, United States, 62702
Actively Recruiting
143
Springfield Clinic
Springfield, Illinois, United States, 62702
Actively Recruiting
144
Springfield Memorial Hospital
Springfield, Illinois, United States, 62781
Actively Recruiting
145
Carle Cancer Center
Urbana, Illinois, United States, 61801
Actively Recruiting
146
Northwestern Medicine Cancer Center Warrenville
Warrenville, Illinois, United States, 60555
Actively Recruiting
147
Illinois CancerCare - Washington
Washington, Illinois, United States, 61571
Suspended
148
Northwest Cancer Center - Crown Point
Crown Point, Indiana, United States, 46307
Suspended
149
UChicago Medicine Northwest Indiana
Crown Point, Indiana, United States, 46307
Actively Recruiting
150
Northwest Oncology LLC
Dyer, Indiana, United States, 46311
Suspended
151
Northwest Cancer Center - Hobart
Hobart, Indiana, United States, 46342
Actively Recruiting
152
Saint Mary Medical Center
Hobart, Indiana, United States, 46342
Suspended
153
Saint Catherine Hospital
Indianapolis, Indiana, United States, 46312
Suspended
154
The Community Hospital
Munster, Indiana, United States, 46321
Suspended
155
Women's Diagnostic Center - Munster
Munster, Indiana, United States, 46321
Suspended
156
Northwest Cancer Center - Valparaiso
Valparaiso, Indiana, United States, 46383
Suspended
157
UI Health Care Mission Cancer and Blood - Ankeny Clinic
Ankeny, Iowa, United States, 50023
Actively Recruiting
158
Saint Anthony Regional Hospital
Carroll, Iowa, United States, 51401
Actively Recruiting
159
Mercy Hospital
Cedar Rapids, Iowa, United States, 52403
Actively Recruiting
160
Oncology Associates at Mercy Medical Center
Cedar Rapids, Iowa, United States, 52403
Actively Recruiting
161
UI Health Care Mission Cancer and Blood - West Des Moines Clinic
Clive, Iowa, United States, 50325
Actively Recruiting
162
Iowa Methodist Medical Center
Des Moines, Iowa, United States, 50309
Actively Recruiting
163
UI Health Care Mission Cancer and Blood - Des Moines Clinic
Des Moines, Iowa, United States, 50309
Actively Recruiting
164
Broadlawns Medical Center
Des Moines, Iowa, United States, 50314
Actively Recruiting
165
UI Health Care Mission Cancer and Blood - Laurel Clinic
Des Moines, Iowa, United States, 50314
Actively Recruiting
166
UI Healthcare Mission Cancer and Blood - Fort Dodge
Fort Dodge, Iowa, United States, 50501
Actively Recruiting
167
UI Health Care Mission Cancer and Blood - Waukee Clinic
Waukee, Iowa, United States, 50263
Actively Recruiting
168
HaysMed
Hays, Kansas, United States, 67601
Actively Recruiting
169
Lawrence Memorial Hospital
Lawrence, Kansas, United States, 66044
Suspended
170
The University of Kansas Cancer Center - Olathe
Olathe, Kansas, United States, 66061
Actively Recruiting
171
Salina Regional Health Center
Salina, Kansas, United States, 67401
Actively Recruiting
172
University of Kansas Health System Saint Francis Campus
Topeka, Kansas, United States, 66606
Actively Recruiting
173
Saint Joseph Hospital East
Lexington, Kentucky, United States, 40509
Actively Recruiting
174
Ochsner Hematology Oncology North Shore - Covington (West Region)
Covington, Louisiana, United States, 70433
Actively Recruiting
175
Ochsner Medical Center Jefferson
New Orleans, Louisiana, United States, 70121
Actively Recruiting
176
UPMC Western Maryland
Cumberland, Maryland, United States, 21502
Actively Recruiting
177
Trinity Health Saint Joseph Mercy Hospital Ann Arbor
Ann Arbor, Michigan, United States, 48106
Actively Recruiting
178
Trinity Health IHA Medical Group Hematology Oncology - Brighton
Brighton, Michigan, United States, 48114
Actively Recruiting
179
Trinity Health Medical Center - Brighton
Brighton, Michigan, United States, 48114
Actively Recruiting
180
Henry Ford Cancer Institute-Downriver
Brownstown, Michigan, United States, 48183
Actively Recruiting
181
Trinity Health IHA Medical Group Hematology Oncology - Canton
Canton, Michigan, United States, 48188
Actively Recruiting
182
Trinity Health Medical Center - Canton
Canton, Michigan, United States, 48188
Actively Recruiting
183
Chelsea Hospital
Chelsea, Michigan, United States, 48118
Actively Recruiting
184
Trinity Health IHA Medical Group Hematology Oncology - Chelsea Hospital
Chelsea, Michigan, United States, 48118
Actively Recruiting
185
Henry Ford Macomb Hospital-Clinton Township
Clinton Township, Michigan, United States, 48038
Actively Recruiting
186
Henry Ford Medical Center-Fairlane
Dearborn, Michigan, United States, 48126
Actively Recruiting
187
Henry Ford Hospital
Detroit, Michigan, United States, 48202
Actively Recruiting
188
OSF Saint Francis Hospital and Medical Group
Escanaba, Michigan, United States, 49829
Actively Recruiting
189
Cancer Hematology Centers - Flint
Flint, Michigan, United States, 48503
Actively Recruiting
190
Genesee Hematology Oncology PC
Flint, Michigan, United States, 48503
Suspended
191
Genesys Hurley Cancer Institute
Flint, Michigan, United States, 48503
Actively Recruiting
192
Hurley Medical Center
Flint, Michigan, United States, 48503
Actively Recruiting
193
Allegiance Health
Jackson, Michigan, United States, 49201
Actively Recruiting
194
University of Michigan Health - Sparrow Lansing
Lansing, Michigan, United States, 48912
Actively Recruiting
195
Trinity Health Saint Mary Mercy Livonia Hospital
Livonia, Michigan, United States, 48154
Actively Recruiting
196
Henry Ford Health Providence Novi Hospital
Novi, Michigan, United States, 48374
Actively Recruiting
197
Henry Ford Medical Center-Columbus
Novi, Michigan, United States, 48377
Actively Recruiting
198
Trinity Health Saint Joseph Mercy Oakland Hospital
Pontiac, Michigan, United States, 48341
Actively Recruiting
199
Henry Ford Health Providence Southfield Hospital
Southfield, Michigan, United States, 48075
Actively Recruiting
200
Henry Ford West Bloomfield Hospital
West Bloomfield, Michigan, United States, 48322
Actively Recruiting
201
Henry Ford Wyandotte Hospital
Wyandotte, Michigan, United States, 48192
Actively Recruiting
202
Trinity Health IHA Medical Group Hematology Oncology Ann Arbor Campus
Ypsilanti, Michigan, United States, 48197
Actively Recruiting
203
Sanford Joe Lueken Cancer Center
Bemidji, Minnesota, United States, 56601
Actively Recruiting
204
Essentia Health Saint Joseph's Medical Center
Brainerd, Minnesota, United States, 56401
Actively Recruiting
205
Mercy Hospital
Coon Rapids, Minnesota, United States, 55433
Actively Recruiting
206
Essentia Health - Deer River Clinic
Deer River, Minnesota, United States, 56636
Actively Recruiting
207
Essentia Health Cancer Center
Duluth, Minnesota, United States, 55805
Actively Recruiting
208
Fairview Southdale Hospital
Edina, Minnesota, United States, 55435
Actively Recruiting
209
Essentia Health Hibbing Clinic
Hibbing, Minnesota, United States, 55746
Actively Recruiting
210
Saint John's Hospital - Healtheast
Maplewood, Minnesota, United States, 55109
Actively Recruiting
211
Abbott-Northwestern Hospital
Minneapolis, Minnesota, United States, 55407
Actively Recruiting
212
Park Nicollet Clinic - Saint Louis Park
Saint Louis Park, Minnesota, United States, 55416
Actively Recruiting
213
Regions Hospital
Saint Paul, Minnesota, United States, 55101
Actively Recruiting
214
United Hospital
Saint Paul, Minnesota, United States, 55102
Actively Recruiting
215
Essentia Health Sandstone
Sandstone, Minnesota, United States, 55072
Actively Recruiting
216
Essentia Health Virginia Clinic
Virginia, Minnesota, United States, 55792
Actively Recruiting
217
Saint Francis Medical Center
Cape Girardeau, Missouri, United States, 63703
Actively Recruiting
218
Siteman Cancer Center at Saint Peters Hospital
City of Saint Peters, Missouri, United States, 63376
Actively Recruiting
219
Siteman Cancer Center at West County Hospital
Creve Coeur, Missouri, United States, 63141
Actively Recruiting
220
University Health Truman Medical Center
Kansas City, Missouri, United States, 64108
Actively Recruiting
221
Washington University School of Medicine
St Louis, Missouri, United States, 63110
Actively Recruiting
222
Siteman Cancer Center-South County
St Louis, Missouri, United States, 63129
Actively Recruiting
223
Siteman Cancer Center at Christian Hospital
St Louis, Missouri, United States, 63136
Actively Recruiting
224
Community Hospital of Anaconda
Anaconda, Montana, United States, 59711
Actively Recruiting
225
Billings Clinic Cancer Center
Billings, Montana, United States, 59101
Actively Recruiting
226
Saint Vincent Frontier Cancer Center
Billings, Montana, United States, 59102
Actively Recruiting
227
Bozeman Health Deaconess Hospital
Bozeman, Montana, United States, 59715
Actively Recruiting
228
Benefis Sletten Cancer Institute
Great Falls, Montana, United States, 59405
Actively Recruiting
229
Logan Health Medical Center
Kalispell, Montana, United States, 59901
Actively Recruiting
230
Community Medical Center
Missoula, Montana, United States, 59804
Actively Recruiting
231
Nebraska Medicine-Bellevue
Bellevue, Nebraska, United States, 68123
Actively Recruiting
232
Nebraska Medicine-Village Pointe
Omaha, Nebraska, United States, 68118
Actively Recruiting
233
University of Nebraska Medical Center
Omaha, Nebraska, United States, 68198
Actively Recruiting
234
OptumCare Cancer Care at Charleston
Las Vegas, Nevada, United States, 89102
Suspended
235
OptumCare Cancer Care at Fort Apache
Las Vegas, Nevada, United States, 89183
Suspended
236
Renown Regional Medical Center
Reno, Nevada, United States, 89502
Actively Recruiting
237
Jefferson Cherry Hill Hospital
Cherry Hill, New Jersey, United States, 08002
Actively Recruiting
238
Englewood Hospital and Medical Center
Englewood, New Jersey, United States, 07631
Active, Not Recruiting
239
Sidney Kimmel Cancer Center Washington Township
Sewell, New Jersey, United States, 08080
Actively Recruiting
240
Lovelace Medical Center-Saint Joseph Square
Albuquerque, New Mexico, United States, 87102
Actively Recruiting
241
University of New Mexico Cancer Center
Albuquerque, New Mexico, United States, 87106
Suspended
242
Northwell Health Imbert Cancer Center
Bay Shore, New York, United States, 11706
Actively Recruiting
243
Roswell Park Cancer Institute
Buffalo, New York, United States, 14263
Actively Recruiting
244
Glens Falls Hospital
Glens Falls, New York, United States, 12801
Actively Recruiting
245
Northwell Health Cancer Institute at Huntington
Greenlawn, New York, United States, 11740
Actively Recruiting
246
Northwell Health/Center for Advanced Medicine
Lake Success, New York, United States, 11042
Actively Recruiting
247
NYU Langone Hospital - Long Island
Mineola, New York, United States, 11501
Actively Recruiting
248
Northern Westchester Hospital
Mount Kisco, New York, United States, 10549
Actively Recruiting
249
Laura and Isaac Perlmutter Cancer Center at NYU Langone
New York, New York, United States, 10016
Actively Recruiting
250
University of Rochester
Rochester, New York, United States, 14642
Actively Recruiting
251
Phelps Memorial Hospital Center
Sleepy Hollow, New York, United States, 10591
Actively Recruiting
252
Cone Health Cancer Center at Asheboro
Asheboro, North Carolina, United States, 27203
Suspended
253
Cone Health MedCenter Asheboro
Asheboro, North Carolina, United States, 27205
Actively Recruiting
254
Cone Health Cancer Center at Alamance Regional
Burlington, North Carolina, United States, 27215
Actively Recruiting
255
Southeastern Medical Oncology Center-Clinton
Clinton, North Carolina, United States, 28328
Actively Recruiting
256
Southeastern Medical Oncology Center-Goldsboro
Goldsboro, North Carolina, United States, 27534
Actively Recruiting
257
Cone Health Cancer Center
Greensboro, North Carolina, United States, 27403
Actively Recruiting
258
Cone Health Cancer Center at Drawbridge Parkway
Greensboro, North Carolina, United States, 27410
Actively Recruiting
259
Southeastern Medical Oncology Center-Jacksonville
Jacksonville, North Carolina, United States, 28546
Actively Recruiting
260
FirstHealth of the Carolinas-Moore Regional Hospital
Pinehurst, North Carolina, United States, 28374
Actively Recruiting
261
Annie Penn Memorial Hospital
Reidsville, North Carolina, United States, 27320
Actively Recruiting
262
Sanford Bismarck Medical Center
Bismarck, North Dakota, United States, 58501
Actively Recruiting
263
Essentia Health Cancer Center-South University Clinic
Fargo, North Dakota, United States, 58103
Actively Recruiting
264
Sanford Broadway Medical Center
Fargo, North Dakota, United States, 58122
Actively Recruiting
265
Sanford Roger Maris Cancer Center
Fargo, North Dakota, United States, 58122
Actively Recruiting
266
Miami Valley Hospital South
Centerville, Ohio, United States, 45459
Actively Recruiting
267
Good Samaritan Hospital - Cincinnati
Cincinnati, Ohio, United States, 45220
Actively Recruiting
268
Miami Valley Hospital
Dayton, Ohio, United States, 45409
Actively Recruiting
269
Premier Blood and Cancer Center
Dayton, Ohio, United States, 45409
Actively Recruiting
270
Miami Valley Hospital North
Dayton, Ohio, United States, 45415
Actively Recruiting
271
Atrium Medical Center-Middletown Regional Hospital
Franklin, Ohio, United States, 45005-1066
Actively Recruiting
272
Miami Valley Cancer Care and Infusion
Greenville, Ohio, United States, 45331
Actively Recruiting
273
Upper Valley Medical Center
Troy, Ohio, United States, 45373
Actively Recruiting
274
Cancer Centers of Southwest Oklahoma Research
Lawton, Oklahoma, United States, 73505
Actively Recruiting
275
University of Oklahoma Health Sciences Center
Oklahoma City, Oklahoma, United States, 73104
Actively Recruiting
276
Integris Southwest Medical Center
Oklahoma City, Oklahoma, United States, 73109
Actively Recruiting
277
Integris Cancer Institute of Oklahoma
Oklahoma City, Oklahoma, United States, 73142
Actively Recruiting
278
Oklahoma Cancer Specialists and Research Institute-Tulsa
Tulsa, Oklahoma, United States, 74146
Actively Recruiting
279
Providence Newberg Medical Center
Newberg, Oregon, United States, 97132
Actively Recruiting
280
Saint Alphonsus Cancer Care Center-Ontario
Ontario, Oregon, United States, 97914
Actively Recruiting
281
Providence Willamette Falls Medical Center
Oregon City, Oregon, United States, 97045
Actively Recruiting
282
Providence Portland Medical Center
Portland, Oregon, United States, 97213
Actively Recruiting
283
Providence Saint Vincent Medical Center
Portland, Oregon, United States, 97225
Actively Recruiting
284
Oregon Health and Science University
Portland, Oregon, United States, 97239
Actively Recruiting
285
Lehigh Valley Hospital-Cedar Crest
Allentown, Pennsylvania, United States, 18103
Actively Recruiting
286
UPMC-Heritage Valley Health System Beaver
Beaver, Pennsylvania, United States, 15009
Actively Recruiting
287
Lehigh Valley Hospital - Muhlenberg
Bethlehem, Pennsylvania, United States, 18017
Actively Recruiting
288
Geisinger Medical Center
Danville, Pennsylvania, United States, 17822
Actively Recruiting
289
Geisinger Cancer Center Dickson City
Dickson City, Pennsylvania, United States, 18519
Actively Recruiting
290
Pocono Medical Center
East Stroudsburg, Pennsylvania, United States, 18301
Actively Recruiting
291
UPMC Hillman Cancer Center Erie
Erie, Pennsylvania, United States, 16505
Actively Recruiting
292
UPMC Cancer Centers - Arnold Palmer Pavilion
Greensburg, Pennsylvania, United States, 15601
Actively Recruiting
293
UPMC Pinnacle Cancer Center/Community Osteopathic Campus
Harrisburg, Pennsylvania, United States, 17109
Actively Recruiting
294
Lehigh Valley Hospital-Hazleton
Hazleton, Pennsylvania, United States, 18201
Actively Recruiting
295
UPMC-Johnstown/John P. Murtha Regional Cancer Center
Johnstown, Pennsylvania, United States, 15901
Actively Recruiting
296
Lancaster General Ann B Barshinger Cancer Institute
Lancaster, Pennsylvania, United States, 17601
Actively Recruiting
297
Geisinger Medical Oncology-Lewisburg
Lewisburg, Pennsylvania, United States, 17837
Actively Recruiting
298
UPMC Hillman Cancer Center at Rocco And Nancy Ortenzio Cancer Pavilion
Mechanicsburg, Pennsylvania, United States, 17050
Actively Recruiting
299
UPMC Hillman Cancer Center - Monroeville
Monroeville, Pennsylvania, United States, 15146
Actively Recruiting
300
Arnold Palmer Cancer Center Medical Oncology Norwin
N. Huntingdon, Pennsylvania, United States, 15642
Actively Recruiting
301
UPMC Hillman Cancer Center - New Castle
New Castle, Pennsylvania, United States, 16105
Actively Recruiting
302
Thomas Jefferson University Hospital
Philadelphia, Pennsylvania, United States, 19107
Actively Recruiting
303
Jefferson Torresdale Hospital
Philadelphia, Pennsylvania, United States, 19114
Actively Recruiting
304
UPMC-Saint Margaret
Pittsburgh, Pennsylvania, United States, 15215
Actively Recruiting
305
University of Pittsburgh Cancer Institute (UPCI)
Pittsburgh, Pennsylvania, United States, 15232
Actively Recruiting
306
UPMC-Passavant Hospital
Pittsburgh, Pennsylvania, United States, 15237
Actively Recruiting
307
UPMC-Saint Clair Hospital Cancer Center
Pittsburgh, Pennsylvania, United States, 15243
Actively Recruiting
308
Community Medical Center
Scranton, Pennsylvania, United States, 18510
Actively Recruiting
309
UPMC Cancer Center at UPMC Northwest
Seneca, Pennsylvania, United States, 16346
Actively Recruiting
310
UPMC Cancer Center-Uniontown
Uniontown, Pennsylvania, United States, 15401
Actively Recruiting
311
Geisinger Wyoming Valley/Henry Cancer Center
Wilkes-Barre, Pennsylvania, United States, 18711
Actively Recruiting
312
Asplundh Cancer Pavilion
Willow Grove, Pennsylvania, United States, 19090
Actively Recruiting
313
Smilow Cancer Hospital Care Center - Westerly
Westerly, Rhode Island, United States, 02891
Actively Recruiting
314
Ralph H Johnson VA Medical Center
Charleston, South Carolina, United States, 29401
Actively Recruiting
315
Medical University of South Carolina
Charleston, South Carolina, United States, 29425
Actively Recruiting
316
Rapid City Regional Hospital
Rapid City, South Dakota, United States, 57701
Actively Recruiting
317
Sanford Cancer Center Oncology Clinic
Sioux Falls, South Dakota, United States, 57104
Actively Recruiting
318
Sanford USD Medical Center - Sioux Falls
Sioux Falls, South Dakota, United States, 57117-5134
Actively Recruiting
319
Vanderbilt University/Ingram Cancer Center
Nashville, Tennessee, United States, 37232
Actively Recruiting
320
Baylor College of Medicine/Dan L Duncan Comprehensive Cancer Center
Houston, Texas, United States, 77030
Actively Recruiting
321
Ben Taub General Hospital
Houston, Texas, United States, 77030
Actively Recruiting
322
Farmington Health Center
Farmington, Utah, United States, 84025
Actively Recruiting
323
University of Utah Sugarhouse Health Center
Salt Lake City, Utah, United States, 84106
Actively Recruiting
324
Huntsman Cancer Institute/University of Utah
Salt Lake City, Utah, United States, 84112
Actively Recruiting
325
Central Vermont Medical Center/National Life Cancer Treatment
Berlin Corners, Vermont, United States, 05602
Active, Not Recruiting
326
University of Vermont Medical Center
Burlington, Vermont, United States, 05401
Active, Not Recruiting
327
University of Vermont and State Agricultural College
Burlington, Vermont, United States, 05405
Active, Not Recruiting
328
VCU Massey Cancer Center at Stony Point
Richmond, Virginia, United States, 23235
Actively Recruiting
329
VCU Massey Comprehensive Cancer Center
Richmond, Virginia, United States, 23298
Actively Recruiting
330
Langlade Hospital and Cancer Center
Antigo, Wisconsin, United States, 54409
Actively Recruiting
331
Duluth Clinic Ashland
Ashland, Wisconsin, United States, 54806
Actively Recruiting
332
Aurora Cancer Care-Southern Lakes VLCC
Burlington, Wisconsin, United States, 53105
Actively Recruiting
333
Aurora Saint Luke's South Shore
Cudahy, Wisconsin, United States, 53110
Actively Recruiting
334
Marshfield Medical Center-EC Cancer Center
Eau Claire, Wisconsin, United States, 54701
Actively Recruiting
335
Aurora Health Care Germantown Health Center
Germantown, Wisconsin, United States, 53022
Actively Recruiting
336
Aurora Cancer Care-Grafton
Grafton, Wisconsin, United States, 53024
Actively Recruiting
337
Saint Vincent Hospital Cancer Center Green Bay
Green Bay, Wisconsin, United States, 54301
Actively Recruiting
338
Saint Vincent Hospital Cancer Center at Saint Mary's
Green Bay, Wisconsin, United States, 54303
Actively Recruiting
339
Aurora BayCare Medical Center
Green Bay, Wisconsin, United States, 54311
Actively Recruiting
340
Aurora Cancer Care-Kenosha South
Kenosha, Wisconsin, United States, 53142
Actively Recruiting
341
William S Middleton VA Medical Center
Madison, Wisconsin, United States, 53705
Actively Recruiting
342
University of Wisconsin Carbone Cancer Center - Eastpark Medical Center
Madison, Wisconsin, United States, 53718
Actively Recruiting
343
University of Wisconsin Carbone Cancer Center - University Hospital
Madison, Wisconsin, United States, 53792
Actively Recruiting
344
Aurora Bay Area Medical Group-Marinette
Marinette, Wisconsin, United States, 54143
Actively Recruiting
345
Marshfield Medical Center-Marshfield
Marshfield, Wisconsin, United States, 54449
Actively Recruiting
346
Aspirus Medford Hospital
Medford, Wisconsin, United States, 54451
Actively Recruiting
347
Aurora Cancer Care-Milwaukee
Milwaukee, Wisconsin, United States, 53209
Actively Recruiting
348
Aurora Saint Luke's Medical Center
Milwaukee, Wisconsin, United States, 53215
Actively Recruiting
349
Aurora Sinai Medical Center
Milwaukee, Wisconsin, United States, 53233
Actively Recruiting
350
Marshfield Medical Center - Minocqua
Minocqua, Wisconsin, United States, 54548
Actively Recruiting
351
ProHealth D N Greenwald Center
Mukwonago, Wisconsin, United States, 53149
Actively Recruiting
352
ProHealth Oconomowoc Memorial Hospital
Oconomowoc, Wisconsin, United States, 53066
Actively Recruiting
353
Saint Vincent Hospital Cancer Center at Oconto Falls
Oconto Falls, Wisconsin, United States, 54154
Actively Recruiting
354
Vince Lombardi Cancer Clinic - Oshkosh
Oshkosh, Wisconsin, United States, 54904
Actively Recruiting
355
Aurora Cancer Care-Racine
Racine, Wisconsin, United States, 53406
Actively Recruiting
356
Aspirus Cancer Care - James Beck Cancer Center
Rhinelander, Wisconsin, United States, 54501
Actively Recruiting
357
Saint Vincent Hospital Cancer Center at Sheboygan
Sheboygan, Wisconsin, United States, 53081
Actively Recruiting
358
Sheboygan Physicians Group
Sheboygan, Wisconsin, United States, 53081
Actively Recruiting
359
Vince Lombardi Cancer Clinic-Sheboygan
Sheboygan, Wisconsin, United States, 53081
Actively Recruiting
360
Aspirus Cancer Care - Stevens Point
Stevens Point, Wisconsin, United States, 54481
Actively Recruiting
361
Marshfield Medical Center-River Region at Stevens Point
Stevens Point, Wisconsin, United States, 54482
Actively Recruiting
362
Saint Vincent Hospital Cancer Center at Sturgeon Bay
Sturgeon Bay, Wisconsin, United States, 54235-1495
Actively Recruiting
363
Aurora Medical Center in Summit
Summit, Wisconsin, United States, 53066
Actively Recruiting
364
Vince Lombardi Cancer Clinic-Two Rivers
Two Rivers, Wisconsin, United States, 54241
Actively Recruiting
365
ProHealth Waukesha Memorial Hospital
Waukesha, Wisconsin, United States, 53188
Actively Recruiting
366
UW Cancer Center at ProHealth Care
Waukesha, Wisconsin, United States, 53188
Actively Recruiting
367
Aspirus Regional Cancer Center
Wausau, Wisconsin, United States, 54401
Actively Recruiting
368
Aurora Cancer Care-Milwaukee West
Wauwatosa, Wisconsin, United States, 53226
Actively Recruiting
369
Aurora West Allis Medical Center
West Allis, Wisconsin, United States, 53227
Actively Recruiting
370
Marshfield Medical Center - Weston
Weston, Wisconsin, United States, 54476
Actively Recruiting
371
Aspirus Cancer Care - Wisconsin Rapids
Wisconsin Rapids, Wisconsin, United States, 54494
Actively Recruiting
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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