Actively Recruiting
Additional Effects of Neural Mobilization on Pain, Balance and Quality of Life in Diabetic Neuropathy
Led by Foundation University Islamabad · Updated on 2025-10-07
32
Participants Needed
1
Research Sites
4 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Diabetic Peripheral Neuropathy (DPN) is a common problem in people with type 2 diabetes, causing symptoms like pain, numbness, and balance difficulties. These issues can lead to falls, foot ulcers, and lower quality of life. Current treatments mainly focus on symptom management, so this study aims to evaluate if adding Neural Mobilization (NM) to balance training can further improve pain, balance, and quality of life in people with DPN. The trial is a randomized controlled study involving 32 patients aged 50 to 75 years. Participants will be randomly assigned to one of two groups for six weeks: one group will receive Neural Mobilization combined with balance training plus standard care, while the other group will receive balance training alone along with standard care. Each group will have two 30-minute sessions per week. The NM protocol includes hot packs, TENS, nerve sliding and tensioning techniques, and various balance exercises that increase in difficulty over time. The balance training group receives similar physical therapy without the neural mobilization techniques. Throughout the study, participants will undergo assessments at the beginning and end of the six-week treatment period. Researchers will measure pain levels using the Numeric Pain Rating Scale, balance using the Berg Balance Scale, and quality of life with the Norfolk Quality of Life-Diabetic Neuropathy questionnaire. Data will be analyzed to determine if adding Neural Mobilization offers additional benefits. Ethical approval has been obtained, and participants will provide informed consent before joining.
CONDITIONS
Brief Title
Additional Effects of Neural Mobilization on Pain, Balance and Quality of Life in Diabetic Neuropathy
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Both genders
- Diagnosed with Diabetic Peripheral Neuropathy
- Age between 50 and 75 years
- History of type 2 Diabetes for at least 5 years
- Presence of neuropathic symptoms such as pain, numbness, tingling, or balance issues
- Mild to moderate pain according to Numeric Pain Rating Scale
You will not qualify if you...
- Neurological disorders like Stroke, multiple sclerosis, or Parkinson's disease
- Chronic pain conditions unrelated to Diabetic Peripheral Neuropathy such as fibromyalgia or osteoarthritis
- Active foot ulcers or infections on lower limbs
- Uncontrolled diabetes
- Severe balance impairment preventing standing unaided for a few seconds
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - 6 weeks
Participants receive Neural Mobilization with Balance Training or Balance Training alone, in addition to conventional physical therapy, to improve pain, balance, and quality of life in diabetic neuropathy.
2 sessions per week, each lasting 30 minutes
Trial Site Locations
Total: 1 location
1
Foundation University College of Physical Therapy
Islamabad, Pakistan, 46000
Actively Recruiting
Research Team
M
Maria Ghulam Fareed, DPT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
Similar Trials
Frequently Asked Questions
Have more questions? Get in touch with our team for quick support
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here