Actively Recruiting
Additional Effects of Neural Mobilization on Pain, Balance and Quality of Life in Diabetic Neuropathy
Led by Foundation University Islamabad · Updated on 2025-10-07
32
Participants Needed
1
Research Sites
69 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Diabetic Peripheral Neuropathy (DPN) is a common complication of diabetes, affecting up to 50% of patients and causing pain, numbness, and balance impairments, which increase the risk of falls, ulcers, and reduced quality of life. Current treatments mainly manage symptoms, highlighting the need for adjunctive approaches. This randomized controlled trial will evaluate the additional effects of Neural Mobilization (NM) on pain, balance, and quality of life in DPN. Thirty-two patients with type 2 diabetes and DPN will be recruited at Fauji Foundation Hospital and screened using the Michigan Neuropathy Screening Instrument (MNSI). Participants will be randomized into two groups: (1) NM plus Balance Training with standard care and (2) Balance Training alone, each for six weeks (two 30-minute sessions/week). Pain will be assessed using the Numeric Pain Rating Scale (NPRS), balance using the Berg Balance Scale, and quality of life using the Norfolk QOL-DN questionnaire. Outcome measures will be recorded at baseline and post-intervention. Ethical approval will be obtained from FUMC ERC, and data will be analyzed using SPSS v.22.
CONDITIONS
Official Title
Additional Effects of Neural Mobilization on Pain, Balance and Quality of Life in Diabetic Neuropathy
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Both genders.
- Diagnosed cases of Diabetic Peripheral Neuropathy.
- Age between 50 and 75 years.
- History of type 2 Diabetes for at least 5 years.
- Presence of neuropathic symptoms including pain, numbness, tingling, or balance issues.
- Mild to moderate pain according to the Numeric Pain Rating Scale (NPRS).
You will not qualify if you...
- Neurological disorders such as stroke, multiple sclerosis, or Parkinson's disease.
- Chronic pain conditions or conditions unrelated to Diabetic Peripheral Neuropathy, including fibromyalgia and osteoarthritis.
- Active foot ulcers or infections on the lower limbs.
- Uncontrolled diabetes.
- Severe balance impairment preventing basic balance tests like standing unaided for a few seconds.
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Foundation University College of Physical Therapy
Islamabad, Pakistan, 46000
Actively Recruiting
Research Team
M
Maria Ghulam Fareed, DPT
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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