Actively Recruiting

Phase Not Applicable
Age: 18Years - 65Years
All Genders
NCT07018726

Addressing Emotional Distress in Dyads of Persons With a Young Onset Dementia (YOD) and Their Care-partners

Led by Massachusetts General Hospital · Updated on 2026-04-15

388

Participants Needed

1

Research Sites

257 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The purpose of the present investigation is to test the efficacy of a virtual, brief (6 sessions) dyadic (patient and care-partner together) intervention to prevent chronic emotional distress in dyads where one person is diagnosed with Young Onset Dementia (YOD). Through this study, we seek to address the unmet need of preventing chronic emotional distress in YOD dyads through a feasible, acceptable and credible program, and ideally enhance resiliency and improve wellbeing and quality of life in both members of the dyad.

CONDITIONS

Official Title

Addressing Emotional Distress in Dyads of Persons With a Young Onset Dementia (YOD) and Their Care-partners

Who Can Participate

Age: 18Years - 65Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Between the ages of 18-65 at the time of enrollment for both patient and care-partner
  • Diagnosis of young-onset dementia (FTD, PPA, AD, PCA, etc.) with symptom onset before age 65 for the patient
  • A designated care-partner willing and interested to participate for both patient and care-partner
  • Received YOD diagnosis in the past 6 months for the patient
  • English fluency and literacy for both patient and care-partner
  • Cognitive ability to understand study and research protocol to consent to participation for both patient and care-partner
  • Patient and/or caregiver show emotional distress on screening with HADS D and/or HADS A scores greater than 7
Not Eligible

You will not qualify if you...

  • Having an additional, terminal diagnosis such as cancer
  • Lack of access to internet and/or a device with a camera
  • Current untreated or unstable severe mental health conditions like bipolar disorder, schizophrenia, or active substance use

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

1
2
3
+1

Trial Site Locations

Total: 1 location

1

Massachusetts General Hospital (MGH)

Boston, Massachusetts, United States, 02114

Actively Recruiting

Loading map...

Research Team

A

Ana-Maria Vranceanu, PhD

CONTACT

M

Maggie L Syme, PhD, MPH

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

DOUBLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

Not the Right Trial for You?

Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.

Already have an account? Log in here

Addressing Emotional Distress in Dyads of Persons With a Young Onset Dementia (YOD) and Their Care-partners | DecenTrialz