Improving Genetic Education and Testing for Hereditary Cancer Risk Among Black Cancer Survivors Using a Chatbot Compared to Usual Care

What this Trial Is About

This research aims to improve genetic education and testing for hereditary cancer risk among Black cancer survivors. It compares a chatbot intervention called a relational agent RA to enhanced usual care EUC to see which approach better encourages genetic education engagement and testing requests. The study also looks at how these methods affect decision-making processes and psychosocial well-being, and explores ways to support family communication of positive genetic test results through a Family Sharing Portal FSP. Participants will be randomly assigned to one of two groups the RA group or the EUC group. The RA group receives a clinical letter and access to the chatbot, which offers tailored genetic education, videos, decision support, and real-time answers, with options to request genetic testing directly through the chatbot. The EUC group receives a clinical letter recommending genetic testing and counseling, with access to clinic websites and support for testing requests. Both groups will have genetic testing results shared with them and their oncologists, with follow-up care tailored accordingly. During the study, participants will complete surveys at baseline, 1 month, and 6 months to assess engagement with genetic education, uptake of genetic testing, decision quality, and psychosocial outcomes. Researchers will monitor how participants use the interventions and their experiences. The study includes adults aged 18 to 80 who self-identify as Black or African American cancer survivors meeting specific criteria. Participation involves online access and comfort with digital tools. The study will last through August 2027, with ongoing data collection and analysis.

Addressing Genomic Disparities in Cancer Survivors