Actively Recruiting
Addressing Neuromuscular Deficits for Improved Outcomes in Ankle Rehabilitation
Led by Phillip Gribble · Updated on 2026-02-20
150
Participants Needed
2
Research Sites
346 weeks
Total Duration
On this page
Sponsors
P
Phillip Gribble
Lead Sponsor
U
United States Department of Defense
Collaborating Sponsor
AI-Summary
What this Trial Is About
The purpose of this project is to compare a novel sensorimotor ankle rehabilitation training (SMART) protocol for Lateral ankle sprains (LASs) against a standard of care (SOC) protocol to determine if it is more successful at producing successful one-year outcomes and lower rates of re-injury and improved health. This will address the identified needs for evidence-support and reintegration strategies to improve understanding of the management of patient rehabilitation strategies throughout the rehabilitation process following neuromusculoskeletal injury. The project will validate an innovative rehabilitation approach while providing metrics of success using a variety of clinical and innovative markers.
CONDITIONS
Official Title
Addressing Neuromuscular Deficits for Improved Outcomes in Ankle Rehabilitation
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Initiating rehabilitation for a first-time acute grade I, II, or III lateral ankle sprain
- Injury sustained within 72 hours before study enrollment
- Diagnosed by a physician, medic, athletic trainer, physical therapist, or other medical personnel as having a lateral ankle sprain
You will not qualify if you...
- Personal or family history of epilepsy or seizures
- History of migraine headaches
- Ocular foreign body, increased intracranial pressure, open head injury, or significant closed head injury
- Cochlear implants
- Implanted brain stimulators, aneurysm clips, or other metal in the head (except mouth)
- Implanted medication pumps, pacemakers, or intracardiac lines
- Current use of tricyclic antidepressants, neuroleptic agents, or other drugs that lower seizure threshold
- History of diagnosed major psychiatric disorder
- History of illicit drug use
- Current alcohol abuse or withdrawal from alcohol abuse
- History of heart disease
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 2 locations
1
University of Kentucky
Lexington, Kentucky, United States, 40506
Actively Recruiting
2
University of North Carolina at Chapel Hill
Chapel Hill, North Carolina, United States, 27599
Actively Recruiting
Research Team
K
Kyle Kosik, PhD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
DOUBLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here