Actively Recruiting

Phase Not Applicable
Age: 18Years - 70Years
All Genders
NCT06319482

The Adherence of Proactive Sleep Apnea Therapy

Led by NovaResp Technologies Inc · Updated on 2024-10-04

200

Participants Needed

1

Research Sites

52 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The goal of this clinical trial is to compare the adherence to Positive Airway Pressure (PAP) therapy for newly diagnosed Obstructive Sleep Apnea (OSA) patients. The main question(s) it aims to answer are: 1. To compare the adherence of proactive therapy and conventional Automatic-PAP (APAP) therapy short-term (3 months) and long-term (12 months) for newly diagnosed OSA patients. 2. To compare health outcomes (AHI, nightly usage, leak, and patient-reported outcomes) between proactive therapy and conventional APAP therapy.

CONDITIONS

Official Title

The Adherence of Proactive Sleep Apnea Therapy

Who Can Participate

Age: 18Years - 70Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Must have a new diagnosis of moderate or severe OSA (i.e., AHI > 15 events/hour).
  • Must be 18-70 years old.
  • No history of self-reported, uncontrolled, severe cardiovascular or neurological issues.
  • Must be able to comply with all study requirements as outlined in the consent form.
  • Must be able to follow the directions of the study doctor and research team.
  • Must be able to understand English and be willing to provide informed consent.
Not Eligible

You will not qualify if you...

  • Prior use of PAP machines.
  • Subjects actively using bi-level PAP or require oxygen therapy.
  • Subjects who are medically complicated or unstable (e.g., cancer, dementia, unstable cardiac or respiratory disease, or unstable psychiatric illness).
  • Potential sleep apnea complications that may affect participant health and safety.
  • Inability or unwillingness to give written informed consent.
  • Neuromuscular disease, hypoglossal-nerve palsy, severe restrictive or obstructive pulmonary disease, moderate-to-severe pulmonary arterial hypertension, severe valvular heart disease, New York Heart Association class III or IV heart failure, recent myocardial infarction or severe cardiac arrhythmias (within 6 months), persistent uncontrolled hypertension despite medication, active psychiatric disease, and coexisting non-respiratory sleep disorders that would confound sleep assessment.
  • Pregnancy, planning to become pregnant, or breastfeeding.

AI-Screening

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Trial Site Locations

Total: 1 location

1

NovaResp Technologies Inc.

Halifax, Nova Scotia, Canada, B3H 4H5

Actively Recruiting

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Research Team

M

Megan Neil, BScN

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

DOUBLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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