Actively Recruiting
Adipose Tissue Blood Flow in Aging Humans
Led by Mayo Clinic · Updated on 2026-05-01
24
Participants Needed
1
Research Sites
254 weeks
Total Duration
On this page
Sponsors
M
Mayo Clinic
Lead Sponsor
N
National Center for Advancing Translational Sciences (NCATS)
Collaborating Sponsor
AI-Summary
What this Trial Is About
The goal of this basic science clinical trial is to understand whether adipose tissue blood flow changes between younger and older healthy adults. The main question\[s\] it aims to answer are: * Is basal and nutrient responsive adipose tissue blood flow (ATBF) different between younger and older adults * What molecular and systemic signatures related to adipose tissue blood flow are altered between these two groups. Participants will undergo measurements of adipose tissue blood flow using the xenon washout technique, undergo 2 abdominal subcutaneous adipose tissue biopsies, and drink a sugary drink.
CONDITIONS
Official Title
Adipose Tissue Blood Flow in Aging Humans
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Be between 18 and 35 years old or between 65 and 80 years old at the time of the study visit
- Have a body mass index (BMI) between 20 and 25.0 kg/m2
You will not qualify if you...
- Diagnosed with cardiometabolic diseases such as Type 2 diabetes, hypertension, or heart failure
- Taking prescription anticoagulants
- Using prescriptions or supplements that affect adipose tissue metabolism (e.g., statins, thiazolidinediones, niacin, atypical antipsychotics, fish oil)
- Pregnant or nursing
- Unable to provide written informed consent
- Currently a smoker
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Mayo Clinic Minnesota
Rochester, Minnesota, United States, 55905
Actively Recruiting
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NON_RANDOMIZED
Model
PARALLEL
Primary Purpose
BASIC_SCIENCE
Number of Arms
2
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