Actively Recruiting

Phase Not Applicable
Age: 12Years - 19Years
All Genders
NCT06973759

Adjunctive Bright Light Therapy in Adolescents With Depression and Eveningness

Led by Chinese University of Hong Kong · Updated on 2026-03-19

90

Participants Needed

1

Research Sites

138 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

This study examines the efficacy of bright light therapy as a treatment for adolescents diagnosed with unipolar non-seasonal depression who exhibit an evening chronotype.

CONDITIONS

Official Title

Adjunctive Bright Light Therapy in Adolescents With Depression and Eveningness

Who Can Participate

Age: 12Years - 19Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Chinese participants aged 12 to 19 years old
  • Written informed assent/consent provided by participant and parent or guardian (if under 18)
  • Diagnosed with unipolar non-seasonal depression confirmed by DSM-5 and K-SADS interview
  • Children's Depression Rating Scale (CDRS-R) score of at least 40
  • Classified as evening chronotype with reduced Horne-Östberg Morning-Eveningness Questionnaire (rMEQ) score below 12
Not Eligible

You will not qualify if you...

  • Current diagnosis of substance abuse or dependence
  • Current or past manic or hypomanic episode, schizophrenia spectrum disorders, organic mental disorders, or intellectual disabilities
  • Clinically significant suicidality with suicidal ideation including plan or attempt
  • Participation in other clinical trial investigational products within one month before study entry
  • Started or changed antidepressant medication within past 4 weeks
  • Currently receiving any structured psychotherapy
  • Hearing or speech deficits
  • Night shift worker
  • Trans-meridian flight across at least two time zones within past 3 months and during the study
  • Presence of eye diseases such as retinal blindness, severe cataract, or glaucoma

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

The Chinese University of Hong Kong

Hong Kong, Hong Kong, Hong Kong, 999077

Actively Recruiting

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Research Team

J

Joey WY Chan

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

DOUBLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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