Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
ID07446127

Evaluation of the Effect of Adjunctive Diode Laser Therapy in Mechanical Scaling and Root Surface Debridement for Non-Surgical Periodontal Therapy

Led by Tel Aviv University · Updated on 2026-03-03

20

Participants Needed

1

Research Sites

N/A

Total Duration

On this page

AI-Summary

What this Trial Is About

Researchers are evaluating the effect of adding diode laser therapy to mechanical, non-surgical root surface cleaning in patients with periodontal disease. The study aims to compare the clinical results of using a 940-nm diode laser along with root surface debridement against root surface debridement alone. This investigation uses a split-mouth design where different parts of the mouth receive different treatments for comparison. In this study, two opposite quadrants of each patient's mouth will receive mechanical scaling and root planing combined with diode laser therapy, while the other two quadrants will undergo mechanical scaling and root planing only. The laser treatment uses a 940-nm diode laser applied adjunctively to the mechanical cleaning. Quadrants are randomly assigned to the treatment groups to ensure unbiased comparison. Participants will be monitored before treatment and then at 12 weeks and 6 months after treatment. Researchers will measure probing pocket depth as the primary outcome and clinical attachment level and bleeding on probing as secondary outcomes. This will help assess and compare the healing and effectiveness of the two treatment approaches over time under regular clinical evaluations.

CONDITIONS

Brief Title

Adjunctive Diode Laser Therapy in Non-Surgical Periodontal Therapy

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Systemically healthy patients
  • Have more than 20 teeth remaining with at least 5 teeth per quadrant
  • Present at least 30% of sites involved with periodontal disease
  • Have at least 2 teeth with a probing depth of 5 mm or more in each quadrant with clear bone loss on X-rays
Not Eligible

You will not qualify if you...

  • History of systemic diseases affecting the gums
  • Smokers and alcoholic patients
  • Use of medications in the last 6 months that might affect gum health
  • Pregnant or breastfeeding women
  • Patients who had periodontal treatment within the last 12 months

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

1 visit (in-person)

Treatment

Duration - 1 day

Participants receive non-surgical periodontal therapy with mechanical root surface debridement, with two quadrants additionally treated with adjunctive diode laser therapy.

1 treatment visit

Follow-up

Duration - 6 months

Participants are assessed to evaluate periodontal health after treatment.

2 visits at 12 weeks and 6 months after treatment

Trial Site Locations

Total: 1 location

1

Dr Younis Mahmoud

Afula, North, Israel, 1839203

Actively Recruiting

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Research Team

M

Mahmoud Dr Younis, DMD

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

SINGLE_GROUP

Primary Purpose

TREATMENT

Number of Arms

2

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Published Research Related To This Trial

Clinical attachment level gain of lasers in scaling and root planing of chronic periodontitis: a network meta-analysis of randomized controlled clinical trials.

Liying Jia, Jinhai Jia, Meng Xie...

https://pubmed.ncbi.nlm.nih.gov/31691054

The Effects of Diode Laser Therapy as an Adjunct to Scaling and Root Planing in the Treatment of Aggressive Periodontitis: A 1-Year Randomized Controlled Clinical Trial.

Giovanni Matarese, Luca Ramaglia, Marco Cicciù...

https://pubmed.ncbi.nlm.nih.gov/28945145

Clinical effectiveness of diode laser therapy as an adjunct to non-surgical periodontal treatment: a randomized clinical study.

Walter Dukić, Ivona Bago, Andrej Aurer...

https://pubmed.ncbi.nlm.nih.gov/23075433

Efficacy of high intensity diode laser as an adjunct to non-surgical periodontal treatment: a randomized controlled trial.

Giorgio De Micheli, Ana Karina Pinto de Andrade, Vanessa Tubero Euzebio Alves...

https://pubmed.ncbi.nlm.nih.gov/20131073

Impact of Adjunctive Diode Laser Application to Non-Surgical Periodontal Therapy on Clinical, Microbiological and Immunological Outcomes in Management of Chronic Periodontitis: A Systematic Review of Human Randomized Controlled Clinical Trials.

Magdalena Pawelczyk-Madalińska, Stefano Benedicenti, Tudor Sălăgean...

https://pubmed.ncbi.nlm.nih.gov/34163210