Actively Recruiting
Adjunctive Effect of Erythritol on Pocket Closure Rates
Led by University of L'Aquila · Updated on 2025-05-06
56
Participants Needed
1
Research Sites
59 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This clinical trial is studying whether using erythritol powder during non-surgical periodontal treatment (deep cleaning) helps improve gum health in people with severe periodontitis. Participants with deep gum pockets (4 mm or more) receive standard treatment alone or standard treatment plus cleaning with erythritol powder. The goal is to evaluate if adding erythritol improves outcomes such as healing of gum pockets, bleeding, plaque levels, and gum attachment compared to standard treatment alone.
CONDITIONS
Official Title
Adjunctive Effect of Erythritol on Pocket Closure Rates
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Adults aged 18 years or older
- Diagnosed with stage 3 or 4 periodontitis according to the 2017 classification
- Presence of at least 12 natural teeth
- Presence of periodontal pockets with probing depth �3e�3d 4 mm in non-adjacent teeth
- Good general health or stable systemic conditions (e.g., controlled diabetes)
You will not qualify if you...
- Use of antibiotics or anti-inflammatory drugs within 3 months prior to treatment
- Periodontal treatment in the previous 6 months
- Pregnancy or breastfeeding
- Current smokers of more than 10 cigarettes per day
- Allergies or intolerance to erythritol or any materials used in the treatment
- Systemic diseases or conditions that could influence periodontal healing (e.g., uncontrolled diabetes, immunodeficiency)
- Use of medications known to affect periodontal tissues (e.g., phenytoin, cyclosporine, calcium channel blockers)
AI-Screening
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Trial Site Locations
Total: 1 location
1
University of L'Aquila
L’Aquila, Italy, 67100
Actively Recruiting
How is the study designed?
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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