Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
Healthy Volunteers
NCT05415111

The Adjunctive Effect of Soft Tissue Augmentation Procedures of Moderate-severe Peri-implantitis

Led by Nadja Naenni · Updated on 2024-05-14

120

Participants Needed

3

Research Sites

369 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The key objective of the study is to compare the effects of soft tissue augmentation using a volume stable collagen matrix or autogenous connective tissue graft or no soft tissue augmentation in addition to bone grafting/implantoplasty in patients who undergo surgical therapy of peri-implantitis with respect to clinical resolution of the infection.

CONDITIONS

Official Title

The Adjunctive Effect of Soft Tissue Augmentation Procedures of Moderate-severe Peri-implantitis

Who Can Participate

Age: 18Years +
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Age > 18 years old (UZH, FRA) or > 21 years old (SIN), male and female
  • Diagnosed with periimplantitis on at least 1 implant in function for at least 1 year
  • Presence of bleeding and/or suppuration on gentle probing
  • Probing depths of 6 mm
  • Bone levels 3 mm apical of the most coronal portion of the intraosseous part of the implant
  • Periodontal health including previously treated periodontitis patients with reduced but healthy periodontium
  • Good oral hygiene with full mouth plaque score <25%
  • Adequate control of inflammation with full mouth bleeding on probing <25%
  • Signed informed consent form
Not Eligible

You will not qualify if you...

  • Pregnant or lactating female patient at inclusion
  • Allergy or objection to porcine and bovine implantable biomaterials
  • Allergy to Penicillin or NSAIDs
  • Known or suspected non-compliance, drug or alcohol abuse
  • Inability to follow the study procedures due to language, comprehension problems, psychological disorders, dementia, etc.
  • Smoking more than 15 cigarettes a day
  • Active periodontal disease

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

1
2
3
+1

Trial Site Locations

Total: 3 locations

1

Department of Oral Surgery and Implantology, Centre for Dentistry and Oral Medicine (Carolinum), Johann Wolfgang Goethe-University Frankfurt

Frankfurt, Germany

Not Yet Recruiting

2

National Dental Centre Singapore

Singapore, Singapore

Not Yet Recruiting

3

Clinic of Reconstructive Dentistry, Center of Dental Medicine University of Zurich

Zurich, Switzerland

Actively Recruiting

Loading map...

Research Team

J

Jolanta Boruta

CONTACT

S

Silvia Rasi, Dr.

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

3

Not the Right Trial for You?

Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.

Already have an account? Log in here

The Adjunctive Effect of Soft Tissue Augmentation Procedures of Moderate-severe Peri-implantitis | DecenTrialz