Actively Recruiting
Adjunctive Keratinized Mucosa Augmentation in Peri-Implantitis
Led by Gazi University · Updated on 2026-03-13
30
Participants Needed
1
Research Sites
65 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This study aims to increase the width and thickness of peri-implant keratinized mucosa (KM) by transferring a properly dimensioned free gingival graft (FGG) from the palatal donor site and to evaluate its effect as an adjunctive approach to non-surgical peri-implantitis therapy. The procedure is indicated for patients diagnosed with peri-implantitis who present with an inadequate KM (midbuccal KM height \< 2 mm). One month after non-surgical therapy, patients in the test group will undergo keratinized mucosa augmentation using an FGG, while patients in the control group will continue with supportive periodontal therapy and regular follow-up visits. The primary outcome measure of the study is the change in probing depth (PD) at 12 months following peri-implantitis treatment.
CONDITIONS
Official Title
Adjunctive Keratinized Mucosa Augmentation in Peri-Implantitis
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Non-smoker
- Systemically healthy
- Keratinized mucosa width less than 2 mm
- Adults aged 18 to 75 years
- Implant-supported restorations in function for at least one year prior to enrollment
You will not qualify if you...
- Use of medications that affect periodontal tissue health and healing
- Pregnancy or lactation
- Smoking 10 or more cigarettes per day
- Untreated periodontitis
- Malpositioned implants
- Previous soft tissue grafting procedures at the implant site
- Systemic conditions affecting wound healing or treatment outcomes (e.g., uncontrolled diabetes, active cancer therapy)
AI-Screening
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Trial Site Locations
Total: 1 location
1
Gazi University Faculty of Dentistry
Ankara, Turkey (Türkiye)
Actively Recruiting
Research Team
S
Sila Cagri Isler, Prof. Dr.
CONTACT
B
Berrin Unsal, Prof Dr
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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