Actively Recruiting
Adjuvant Chemotherapy and Immunotherapy for Completely Resected Small Cell Lung Cancer
Led by Alliance Foundation Trials, LLC. · Updated on 2026-02-17
65
Participants Needed
1
Research Sites
260 weeks
Total Duration
On this page
Sponsors
A
Alliance Foundation Trials, LLC.
Lead Sponsor
A
AstraZeneca
Collaborating Sponsor
AI-Summary
What this Trial Is About
This is a phase II trial of adjuvant chemotherapy and immunotherapy for completely resected small cell lung cancer (SCLC).
CONDITIONS
Official Title
Adjuvant Chemotherapy and Immunotherapy for Completely Resected Small Cell Lung Cancer
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age 18 years or older
- Body weight greater than 30 kg
- Life expectancy of at least 12 weeks
- Confirmed diagnosis of pathologic T1-T2 N0-1 M0 small-cell lung cancer
- Complete surgical removal of small-cell lung cancer within 78 days prior to enrollment
- Complete mediastinal lymph node dissection or systematic sampling performed
- No prior systemic therapy for small cell lung cancer
- Post-operative radiation allowed for N1 disease as per physician
- ECOG performance status of 0 or 1
You will not qualify if you...
- Receiving any other investigational agents
- Enrolled in another clinical study with investigational treatment for small cell lung cancer
- Prior treatment with durvalumab
- History of another primary cancer except certain treated low-risk cancers without active disease for at least 2 years
- History of cerebrovascular accident, pulmonary embolism, or untreated deep venous thrombosis within past 3 months
- Hemoptysis exceeding 2.5 mL within 2 weeks before first study treatment
- Need for concurrent treatment with phenytoin, phenobarbital, or carbamazepine
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
University of Virginia Comprehensive Cancer Center
Charlottesville, Virginia, United States, 22908
Actively Recruiting
Research Team
Q
Quality Management and Compliance
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
TREATMENT
Number of Arms
1
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