Study Evaluating HPV Vaccination After Surgery to Prevent Recurrence of Cervical Dysplasia

What this Trial Is About

Researchers are evaluating the role of HPV vaccination in women who have undergone surgery for HPV-related cervical lesions, specifically looking at its potential to reduce the risk of recurrence after excisional treatment. This observational study aims to monitor and compare the risk of HPV recurrence in women who choose to receive the vaccine versus those who do not. The study is sponsored by Fondazione IRCCS Istituto Nazionale dei Tumori, Milano. Participants include women treated for HPV-related disease, some of whom will receive HPV vaccination as an additional step after surgery, while others will not. The study observes the natural course of recurrence risk based on vaccination status without administering assigned treatments. This approach allows researchers to assess the vaccines impact in a real-world setting over time. Throughout the study, participants will be monitored for HPV recurrence over a two-year period following treatment. Data collection will include medical follow-up visits and evaluations to track recurrence rates. The study aims to provide information on whether vaccination after surgery helps prevent HPV from returning, with all care and monitoring conducted under medical supervision during the participation period.

Adjuvant VaccInation After Conization for the Treatment for CervicAL Dysplasia