Feasibility Study Using fMRI to Compare Brain Activity in Adolescent Girls with Borderline Personality Disorder, ADHD, or No Psychological Disorders

What this Trial Is About

Researchers are studying brain activity related to borderline personality disorder BPD and other clinical conditions in adolescent girls using functional magnetic resonance imaging fMRI. This feasibility study aims to increase understanding of the brain patterns linked with BPD and related disorders, building on earlier research conducted in Quebec. The study includes girls with BPD, girls with Attention Deficit Hyperactivity Disorder ADHD, and healthy volunteers without psychiatric disorders. Participants will undergo fMRI scans as part of the study. The three groupsadolescent girls with BPD, those with ADHD, and healthy controlswill follow the same study plan involving brain imaging sessions. The study is non-randomized and single-blinded, focusing on comparing brain activation patterns among these groups to assess the feasibility and neural correlates of BPD. Throughout the study, participants will be evaluated using MRI-acquired activation mapping over two years. Researchers will assess brain function and feasibility measures while monitoring participant health. The total duration includes imaging and clinical evaluations, with participants being adolescent girls aged 12 to 17 who are stable at the time of testing. Safety considerations such as avoiding participation with contraindications to MRI are included in the monitoring process.

ADOLESCENTS IMAGING USING fMRI: Feasibility Study