Actively Recruiting

Phase 1
All Genders
NCT03391778

Adoptive Cell Therapy Long-term Follow-up (LTFU) Study

Led by USWM CT, LLC · Updated on 2026-03-03

250

Participants Needed

24

Research Sites

729 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

This trial will evaluate long term safety of participants who have received AdaptImmune (ADP) adoptive cell therapy for up to 15 years following last adoptive cell therapy infusion.

CONDITIONS

Official Title

Adoptive Cell Therapy Long-term Follow-up (LTFU) Study

Who Can Participate

All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Participants who have received at least one dose of ADP adoptive cell therapy agent.
  • Participants who have completed ADP sponsored or supported interventional study or have withdrawn from it.
  • Participants who have completed treatment as part of managed access to a GSK adoptive cell therapy.
  • Contraceptive use by men or women should be consistent with local regulations regarding the methods of contraception for those participating in clinical studies.
  • The investigator is responsible for review of medical history.
  • Capable of giving signed informed consent.
Not Eligible

You will not qualify if you...

History of severe allergic reactions to study medication Currently pregnant or breastfeeding Recent participation in another clinical trial within the last 30 days Presence of uncontrolled medical conditions that could affect safety

AI-Screening

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Trial Site Locations

Total: 24 locations

1

Emory University School of Medicine

Atlanta, Georgia, United States, 30322

Actively Recruiting

2

ADP Investigational Site

Baltimore, Maryland, United States, 21201

Actively Recruiting

3

National Cancer Institute - Center for Cancer Research

Bethesda, Maryland, United States, 20892

Completed

4

University of Michigan

Ann Arbor, Michigan, United States, 48109

Actively Recruiting

5

Washington University School of Medicine in St. Louis

St Louis, Missouri, United States, 63110

Actively Recruiting

6

Memorial Sloan Kettering Cancer Center - New York

New York, New York, United States, 10065

Actively Recruiting

7

Duke University Medical Center

Durham, North Carolina, United States, 27710

Actively Recruiting

8

Oregon Health and Science University

Portland, Oregon, United States, 97239

Actively Recruiting

9

University of Pennsylvania

Philadelphia, Pennsylvania, United States, 19104

Actively Recruiting

10

University of Pittsburgh Medical Center (UPMC) Hillman Cancer Center

Pittsburgh, Pennsylvania, United States, 15232

Actively Recruiting

11

University of Texas Southwestern Medical Center

Dallas, Texas, United States, 75390

Actively Recruiting

12

University of Texas MD Anderson Cancer Center

Houston, Texas, United States, 77030

Actively Recruiting

13

Froedtert Hospital

Milwaukee, Wisconsin, United States, 53226

Actively Recruiting

14

Peter MacCallum Cancer Centre

Melbourne, Victoria, Australia, 3000

Actively Recruiting

15

Princess Margaret Cancer Centre

Toronto, Ontario, Canada, M5G 2M9

Actively Recruiting

16

Hôpital Maisonneuve-Rosemont

Montreal, Quebec, Canada, H1T 2M4

Actively Recruiting

17

Klinikum rechts der Isar der Technischen Universität München

Munich, Bavaria, Germany, 81377

Actively Recruiting

18

Uniklinik Köln

Cologne, North Rhine-Westphalia, Germany, 50937

Actively Recruiting

19

Fondazione IRCCS - Istituto Nazionale dei Tumori

Milan, Lombardy, Italy, 20133

Actively Recruiting

20

Antoni Van Leeuwenhoek Ziekenhuis

Amsterdam, Netherlands, 1066 CX

Actively Recruiting

21

Hospital Universitario Virgen del Rocío

Seville, Spain, 41013

Actively Recruiting

22

University College London Hospitals NHS Foundation Trust

London, United Kingdom, NW1 2PG

Actively Recruiting

23

USWM CT Investigational Site

Manchester, United Kingdom, M20 4BX

Actively Recruiting

24

The Royal Marsden NHS Foundation Trust

Sutton, United Kingdom, SM2 5PT

Actively Recruiting

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Research Team

I

Investigator Study Inquiries LTFU

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

OTHER

Number of Arms

1

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