Actively Recruiting

Age: 18Years +
All Genders
ID06279442

Adrenal Project: Clinical and Epidemiological Characterization of Adrenocortical Carcinoma in a Brazilian Cohort

Led by Latin American Cooperative Oncology Group · Updated on 2025-02-12

150

Participants Needed

10

Research Sites

N/A

Total Duration

On this page

AI-Summary

What this Trial Is About

Researchers are conducting a retrospective observational cohort study to evaluate clinical, pathological, and treatment data of people diagnosed with adrenocortical carcinoma since the year 2000. This rare cancer has a notably higher incidence in certain regions of Brazil, partly due to a common genetic mutation called TP53-R337H. The study aims to characterize this patient group and identify factors that influence outcomes, focusing on cases from major Brazilian treatment centers. Participants in this study are identified based on past clinical records rather than receiving new treatments. The study collects data from medical evaluations and follow-ups conducted at reference centers, including initial diagnosis and recurrences from 2000 onward. There are no interventions or experimental treatments given during this observational study. Participants' involvement includes reviewing their medical history and clinical data over approximately 18 months. Researchers will analyze demographic and clinical characteristics from existing records to better understand the disease in this population. The study does not involve active treatment but focuses on data collection and analysis for improved knowledge of adrenocortical carcinoma in Brazil.

CONDITIONS

Brief Title

Adrenal Project: Clinical and Epidemiological Characterization of Adrenocortical Carcinoma in a Brazilian Cohort

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Participants over 18 years old
  • Diagnosis of adrenocortical carcinoma with at least one clinical evaluation at the reference institution
  • Initial diagnosis or recurrence from the year 2000 onwards
Not Eligible

You will not qualify if you...

  • Participants with insufficient clinical or pathological data in the medical records

AI-Screening

AI-Powered Screening

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Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

1 visit (in-person)

Long-term Monitoring

Duration - Approximately 18 months

Participants with adrenocortical carcinoma are observed to characterize clinical and epidemiological features over time.

Visits occur as part of routine clinical evaluations

Trial Site Locations

Total: 10 locations

1

Pronutrir - Suporte Nutricional e Quimioterapia

Fortaleza, Ceará, Brazil, 60.810-180

Actively Recruiting

2

Hospital do Câncer do Maranhão Dr. Tarquínio Lopes Filho

São Luís, Maranhão, Brazil, 65.015-460

Actively Recruiting

3

Hospital Erasto Gaertner

Curitiba, Paraná, Brazil, 81.520-060

Actively Recruiting

4

Hospital Santa Joana Recife (Instituto Américas PE)

Recife, Pernambuco, Brazil, 52.011-000

Actively Recruiting

5

UOPECCAN - Hospital do Câncer de Cascavel

Cascavel, Santa Catarina, Brazil, 85.806-300

Actively Recruiting

6

FUNFARME - Hospital de Base de São José do Rio Preto

São José do Rio Preto, São Paulo, Brazil, 15.090-000

Actively Recruiting

7

INCA - Instituto Nacional de Câncer

Rio de Janeiro, Brazil, 20.230-130

Actively Recruiting

8

BP - A Beneficência Portuguesa de São Paulo

São Paulo, Brazil, 01.323-030

Actively Recruiting

9

HAOC - Hospital Alemão Oswaldo Cruz

São Paulo, Brazil, 01.327-001

Actively Recruiting

10

A.C. Camargo Cancer Center

São Paulo, Brazil, 01.509-001

Actively Recruiting

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Research Team

G

Giana Blume Corssac

L

Laura Voelcker

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

0

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