Use of Advanced Fixation Dressings in Reducing Central Venous Catheter-related Bloodstream Infections in a Paediatric Intensive Care Unit

What this Trial Is About

Researchers are evaluating two types of transparent dressings used on central venous catheters (CVCs) to prevent bloodstream infections in children admitted to a pediatric intensive care unit (PICU). This randomized, single-blind trial compares dressings impregnated with chlorhexidine gluconate to conventional transparent dressings. The study aims to understand which dressing better reduces catheter-related infections, catheter colonization, skin complications, and the frequency of dressing changes. Participants will be randomly assigned to receive either the advanced chlorhexidine gluconate-impregnated transparent dressing or the standard transparent polyurethane dressing without antimicrobial properties at the catheter insertion site. The chlorhexidine dressing provides sustained antimicrobial protection while allowing visibility of the site and may reduce the need for frequent catheter manipulation. Both dressings are applied at the central venous catheter insertion area and monitored during the study period. During the study, participants will be observed from baseline up to four weeks or until catheter removal, whichever occurs first. Researchers will track infection rates, catheter colonization at removal (up to 14 days after insertion), skin issues at the insertion site, and how often dressings need changing. The study involves careful monitoring of the catheter site and overall health while participating, with safety and infection outcomes recorded throughout the follow-up period.

Advanced Dressings for CVC Infection Prevention in PICU