Registry Study on Advanced Endoscopic Treatments for Gastrointestinal Diseases Including EMR, ESD, RFA, APC, and POEM Procedures

What this Trial Is About

Researchers are observing advanced therapeutic endoscopy procedures used to treat gastrointestinal GI diseases with minimal invasiveness. This registry-based study at the Centre Hospitalier de lUniversite9 de Montre9al aims to improve the quality of advanced endotherapeutic practices by collecting data on common procedures such as endoscopic mucosal resection EMR, endoscopic mucosal dissection ESD, radio frequency ablation RFA, argon plasma coagulation APC, and per oral endoscopic myotomy POEM. The study focuses on both benign and malignant GI conditions, including colorectal polyps and cancers, and the Zenker diverticulum. The study collects prospective data on patients undergoing various advanced endoscopic treatments including EMR, which removes mucosal lesions ESD, which involves precise submucosal dissection RFA and APC, which use thermal energy to destroy tissue and POEM, an endoscopic myotomy technique for esophageal conditions. Data are recorded on case report forms and stored securely in an electronic registry to assess treatment quality and outcomes. This observational study does not involve experimental drug administration but monitors real-world clinical procedures. Participants involvement includes undergoing their scheduled advanced endoscopic procedures while data related to their treatments and outcomes are collected. Researchers evaluate short-term outcomes such as severe complications, bleeding, and perforation within 14 days, as well as longer-term measures including resection completeness, recurrence, metastasis, survival, and quality of life over 6 to 18 months. Data protection and continuous monitoring support the assessment of procedural quality and patient safety throughout the study period, which extends until late 2026.

Advanced Endo-therapeutic Procedure : Registry-based Observational Study