Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
NCT02613988

Advanced MR Imaging as Predictor of Treatment Response in Newly Diagnosed Glioblastomas

Led by Asan Medical Center · Updated on 2024-05-14

100

Participants Needed

1

Research Sites

307 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

This clinical trial studies advanced MR imaging techniques in measuring early response of standard treatment may become predictors of long-term treatment response in patients with newly diagnosed glioblastomas.

CONDITIONS

Official Title

Advanced MR Imaging as Predictor of Treatment Response in Newly Diagnosed Glioblastomas

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Patients must have radiologically and histologically confirmed diagnosis of newly diagnosed glioblastoma
  • Patients must have measurable disease, defined as evident tumors with gadolinium enhancement on MRI that is measurable in at least one diameter
  • Life expectancy of greater than 3 months
  • Patients scheduled for standard therapy (6 weeks radiation treatment (~ 60 Gy) plus temozolomide 75 mg/m2 during 6 week RT, and followed by routine monthly temozolomide therapy)
  • Ability to understand and the willingness to sign a written informed consent document; all patients, or their legal guardians, must sign a written informed consent and Health Insurance Portability and Accountability Act (HIPAA) authorization in accordance with institutional guidelines
Not Eligible

You will not qualify if you...

  • Patients who underwent complete resection
  • Patients with no evidence of measurable disease after surgery
  • Patients who have had chemotherapy or radiotherapy
  • Patients who have any type of bioimplant activated by mechanical, electronic, or magnetic means (e.g., cochlear implants, pacemakers, neurostimulators, electronic infusion pumps, etc)
  • Patients who are pregnant or breast feeding; urine pregnancy test will be performed on women of child bearing potential
  • Patients with baseline MR images that exhibit enough signal degradation from surgical artifacts making data uninterpretable

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Asan Medical Center

Seoul, South Korea

Actively Recruiting

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Research Team

H

Ho Sung Kim, MD, PhD

CONTACT

J

Ji Eun Park, MD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

DIAGNOSTIC

Number of Arms

1

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