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Study of Advanced Technologies for Successful Atrial Fibrillation Ablation in Clinical Practice Evaluating long-term outcomes and predictors after AF catheter ablation

Led by Giulio Zucchelli · Updated on 2022-11-15

4100

Participants Needed

1

Research Sites

56 weeks

Total Duration

AI-Summary

What this Trial Is About

Atrial fibrillation AF is the most common heart rhythm disorder worldwide, affecting about 3% of adults and expected to increase due to longer lifespans and more diagnoses. This study aims to prospectively evaluate a large group of patients undergoing AF ablation to identify clinical and procedural factors that predict success in preventing arrhythmia recurrence over the medium to long term. The main goal is to determine which parameters best predict freedom from clinical atrial arrhythmias 12 months after the procedure. Patients with indications for AF ablation will receive treatment following standard care at participating centers. The study collects data on procedural success immediately after ablation and tracks patients for 12 months to monitor for arrhythmia recurrence, other atrial arrhythmias, and any adverse events. The study will also assess patient-reported outcomes, ECG changes before and after ablation, and healthcare resource use. This observational study enrolls consecutive patients meeting eligibility criteria without altering their treatment plan. Participants will be followed for 12 months after their ablation procedure, with data collected on clinical history, drug therapy, arrhythmia recurrences, adverse events, and patient symptoms. Evaluations include acute procedural success, ECG monitoring, and questionnaires on quality of life and symptom severity. Researchers will analyze these data to identify factors associated with long-term success and safety of AF ablation. This study provides real-world insights into the management and outcomes of patients undergoing AF ablation over time.

CONDITIONS

Brief Title

Advanced TecHnologies For SuccEssful AblatioN of AF in Clinical Practice

Research Team

G

Giulio Zucchelli, MD, PhD

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