+1 877 705 191424 / 7
HIPAA Compliant
ISO 27001 Certified

Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
ID07152249

Improving Postoperative Nausea and Vomiting Prevention Using a Clinical Decision Support Tool During Surgery with General Anesthesia

Led by Vanderbilt University Medical Center · Updated on 2026-01-12

19480

Participants Needed

1

Research Sites

N/A

Total Duration

AI-Summary

What this Trial Is About

Researchers are evaluating whether a new clinical decision support CDS tool integrated into the electronic health record can improve the prevention of postoperative nausea and vomiting PONV in adults undergoing planned surgery with general anesthesia. The study aims to see if this tool increases the appropriate use of PONV prevention and lowers the rate of PONV compared to standard care. The trial uses a repeated crossover design over 12 months to test the tools impact on clinical practice and patient outcomes. The intervention involves the AW-D Clinical Decision Support Tool, which delivers automated reminders to anesthesia providers at key times during surgery, such as before surgery starts, after anesthesia induction, and before the patient wakes up. These alerts are personalized based on each patients risk factors for PONV and serve as reminders rather than mandates. The study alternates between periods when the tool is active and when it is not, including washout and control phases. Participants will be adult patients undergoing general anesthesia with planned surgery. Researchers will monitor how often PONV prevention medications are given appropriately during surgery and track the incidence of PONV within three hours after surgery. They will also measure the length of stay in the post-anesthesia care unit PACU. The study involves no direct intervention on patients beyond standard care and data collection. The total participation duration varies with each surgical case and immediate postoperative period.

CONDITIONS

Brief Title

Advancing Strategies to Optimize the PerIopeRativE Management of PostOperative Nausea and Vomiting (ASPIRE-PONV) Trial

Research Team

M

Miklos Kertai, M.D., Ph.D.

G

Gail Mayo

Not the Right Trial for You?

Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.

Already have an account? Log in here