Actively Recruiting

Phase Not Applicable
Age: 65Years - 100Years
All Genders
NCT06192082

Adverse Cardiovascular Events During Painless Gastroscopy Diagnosis and Treatment in Elderly Frail Patients

Led by Beijing Friendship Hospital · Updated on 2026-02-12

226

Participants Needed

1

Research Sites

110 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

This study aims to compare the effects of conscious sedation and intravenous general anesthesia on cardiovascular events in frail patients undergoing digestive endoscopy diagnosis and treatment.

CONDITIONS

Official Title

Adverse Cardiovascular Events During Painless Gastroscopy Diagnosis and Treatment in Elderly Frail Patients

Who Can Participate

Age: 65Years - 100Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Age greater than 65 years old
  • ASA classified as Class II or III
  • Body mass index between 18 and 28 kg/m2
  • Undergoing digestive endoscopy examination or treatment outside an operating room
  • FRAIL scale score of 3 points or higher
  • Voluntary participation with signed informed consent
Not Eligible

You will not qualify if you...

  • Allergy or contraindications to benzodiazepines, opioids, propofol, or their components
  • Acute heart failure
  • Unstable angina pectoris
  • Myocardial infarction within 6 months before screening
  • Resting heart rate less than 50 beats per minute on electrocardiogram
  • Third degree atrioventricular block
  • Severe arrhythmia
  • Moderate to severe heart valve disease
  • Severe respiratory diseases such as acute respiratory infections, acute COPD exacerbations, uncontrolled asthma
  • No formal antihypertensive treatment or uncontrolled blood pressure
  • Traumatic brain injury, possible intracranial hypertension, cerebral aneurysms, history of stroke, or central nervous system diseases
  • Mental disorders including schizophrenia, mania, bipolar disorder, cognitive impairment, or long-term psychotropic drug use
  • Other conditions deemed unsuitable by the researcher

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Beijing Friendship Hospital, Capital Medical University

Beijing, Beijing Municipality, China, 100050

Actively Recruiting

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Research Team

H

Haijun Hou, MD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

DOUBLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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