Study Comparing Effects of Conscious Sedation and Intravenous General Anesthesia on Heart Events During Painless Gastroscopy in Elderly Frail Patients

What this Trial Is About

This research aims to compare how conscious sedation and intravenous general anesthesia affect cardiovascular events in elderly frail patients undergoing digestive endoscopy for diagnosis and treatment. The study focuses on patients aged 65 to 100 years who are considered frail and need this procedure outside of an operating room setting. It seeks to understand which anesthesia method might be safer or cause fewer heart-related problems during these procedures. Participants are randomly assigned to one of two groups. The conscious sedation group receives sufentanil and midazolam before the procedure, with sedation levels monitored and adjusted as needed during the endoscopy. The intravenous general anesthesia group receives sufentanil and propofol, with doses tailored based on the patients sleep depth and tolerance to the procedure. Both groups undergo continuous monitoring of heart rate, blood pressure, oxygen levels, and electrocardiograms during and shortly after the procedure. During the study, patients will have regular measurements of vital signs and heart monitoring, with any abnormalities recorded until the endoscope is removed. Researchers will collect feedback on satisfaction from patients, gastroenterologists, and anesthesiologists. Follow-up calls within three days will check for any side effects like dizziness, headache, or nausea. The main outcome measured is the occurrence of adverse cardiovascular events during the procedure and recovery period, with additional assessments of other side effects, pain scores, and satisfaction levels.

Adverse Cardiovascular Events During Painless Gastroscopy Diagnosis and Treatment in Elderly Frail Patients