Actively Recruiting

Phase Not Applicable
Age: 20Years - 60Years
All Genders
ID07414615

The Effect of Aerobic Training on Gait, Postural Control, Lower Extremity Muscle Strength and Functionality in Patients With Lower Extremity Lymphedema

Led by Bezmialem Vakif University · Updated on 2026-02-19

24

Participants Needed

1

Research Sites

N/A

Total Duration

On this page

AI-Summary

What this Trial Is About

Researchers are evaluating the effects of aerobic exercise training on walking, balance, muscle strength, and functional ability in adults with bilateral lower extremity lymphedema. This condition causes swelling and tissue changes in the legs due to lymph fluid buildup, often resulting from cancer treatments or other causes. The study aims to compare the benefits of aerobic exercise combined with Complex Decongestive Therapy (CDT) against CDT alone in improving these physical functions. Participants will be randomly assigned to one of two groups: one receiving standard Complex Decongestive Physiotherapy (CDP) five days a week for six weeks, including manual lymphatic drainage, compression bandaging, skin care, and therapeutic exercises; the other group will receive the same CDP plus 20 minutes of aerobic training on a recumbent cycle ergometer at moderate intensity, followed by a cool-down period. Exercises during CDP involve movements targeting the hips, knees, and ankles performed under supervision. Throughout the study, researchers will assess leg swelling, walking speed, step length, balance, muscle strength, endurance, and overall lower limb function using various tests at the start and end of the 6-week intervention. These include circumference measurements, gait analysis software, balance scoring systems, muscle testing, and functional questionnaires. The study will monitor participant progress and safety, with the total duration of participation being six weeks.

CONDITIONS

Brief Title

Aerobic Training in Lower Extremity Lymphedema

Who Can Participate

Age: 20Years - 60Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Aged between 20 and 60 years
  • Diagnosed with bilateral lower extremity lymphedema
  • Completed chemotherapy, radiotherapy, or other cancer treatments with no oncological contraindication
  • Signed written informed consent
  • Willingness to participate in the study
Not Eligible

You will not qualify if you...

  • Presence of uncontrolled cardiac or pulmonary disease
  • Presence of renal insufficiency
  • Musculoskeletal or neurological disorders affecting mobility or balance
  • Systemic or local infection in the lower extremity
  • Impaired independent ambulation or use of assistive walking devices
  • Pregnancy
  • Visual, cognitive, or intellectual impairment interfering with study participation

AI-Screening

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Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

1 visit (in-person)

Treatment

Duration - 6 weeks

Participants will receive Complex Decongestive Physiotherapy five days per week for six weeks. Those in the combined group will also complete a structured aerobic training program on a recumbent cycle ergometer during this period.

5 visits per week (in-person) during treatment

Trial Site Locations

Total: 1 location

1

Bezmialem Vakif University

Istanbul, Turkey (Türkiye)

Actively Recruiting

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Research Team

D

Deniz Tuncer, PhD, PT

S

Serra Undil-Erdogmus, PT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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