Actively Recruiting
The Effect of Aerobic Training on Gait, Postural Control, Lower Extremity Muscle Strength and Functionality in Patients With Lower Extremity Lymphedema
Led by Bezmialem Vakif University · Updated on 2026-02-19
24
Participants Needed
1
Research Sites
N/A
Total Duration
On this page
AI-Summary
What this Trial Is About
Researchers are evaluating the effects of aerobic exercise training on walking, balance, muscle strength, and functional ability in adults with bilateral lower extremity lymphedema. This condition causes swelling and tissue changes in the legs due to lymph fluid buildup, often resulting from cancer treatments or other causes. The study aims to compare the benefits of aerobic exercise combined with Complex Decongestive Therapy (CDT) against CDT alone in improving these physical functions. Participants will be randomly assigned to one of two groups: one receiving standard Complex Decongestive Physiotherapy (CDP) five days a week for six weeks, including manual lymphatic drainage, compression bandaging, skin care, and therapeutic exercises; the other group will receive the same CDP plus 20 minutes of aerobic training on a recumbent cycle ergometer at moderate intensity, followed by a cool-down period. Exercises during CDP involve movements targeting the hips, knees, and ankles performed under supervision. Throughout the study, researchers will assess leg swelling, walking speed, step length, balance, muscle strength, endurance, and overall lower limb function using various tests at the start and end of the 6-week intervention. These include circumference measurements, gait analysis software, balance scoring systems, muscle testing, and functional questionnaires. The study will monitor participant progress and safety, with the total duration of participation being six weeks.
CONDITIONS
Brief Title
Aerobic Training in Lower Extremity Lymphedema
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Aged between 20 and 60 years
- Diagnosed with bilateral lower extremity lymphedema
- Completed chemotherapy, radiotherapy, or other cancer treatments with no oncological contraindication
- Signed written informed consent
- Willingness to participate in the study
You will not qualify if you...
- Presence of uncontrolled cardiac or pulmonary disease
- Presence of renal insufficiency
- Musculoskeletal or neurological disorders affecting mobility or balance
- Systemic or local infection in the lower extremity
- Impaired independent ambulation or use of assistive walking devices
- Pregnancy
- Visual, cognitive, or intellectual impairment interfering with study participation
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - 6 weeks
Participants will receive Complex Decongestive Physiotherapy five days per week for six weeks. Those in the combined group will also complete a structured aerobic training program on a recumbent cycle ergometer during this period.
5 visits per week (in-person) during treatment
Trial Site Locations
Total: 1 location
1
Bezmialem Vakif University
Istanbul, Turkey (Türkiye)
Actively Recruiting
Research Team
D
Deniz Tuncer, PhD, PT
S
Serra Undil-Erdogmus, PT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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