Actively Recruiting
Aerobic Training in Lower Extremity Lymphedema
Led by Bezmialem Vakif University · Updated on 2026-02-19
24
Participants Needed
1
Research Sites
7 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This randomized controlled study aims to evaluate the effects of aerobic exercise training on gait, postural control, lower extremity muscle strength, and functional status in individuals with bilateral lower extremity lymphedema. A total of 24 participants aged between 20 and 60 years with a diagnosis of bilateral lower extremity lymphedema will be randomly assigned to either an aerobic exercise group or a control group. The aerobic exercise group will receive aerobic exercise training in addition to Complex Decongestive Therapy (CDT), while the control group will receive CDT alone. Lower extremity edema will be assessed using circumferential measurements taken from the ankle to the inguinal region. Gait function will be evaluated through angular and spatiotemporal analysis using Kinovea software, including parameters such as step length, walking speed, and double support time. Postural control will be assessed using the Balance Error Scoring System (BESS) and the Timed Up and Go Test. Lower extremity muscle strength and endurance will be evaluated using Manual Muscle Testing and the 30-Second Sit-to-Stand Test. Functional status of the lower extremities will be assessed using the Lower Extremity Functional Scale (LEFS).
CONDITIONS
Official Title
Aerobic Training in Lower Extremity Lymphedema
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Aged between 20 and 60 years
- Diagnosed with bilateral lower extremity lymphedema
- Completed chemotherapy, radiotherapy, or other cancer treatments with no contraindications
- Provided signed informed consent
- Willing to participate in the study
You will not qualify if you...
- Uncontrolled heart or lung disease
- Kidney failure
- Musculoskeletal or neurological disorders affecting movement or balance
- Infection in the lower leg
- Unable to walk independently or requires walking aids
- Pregnant
- Visual, cognitive, or intellectual impairments interfering with study participation
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Bezmialem Vakif University
Istanbul, Turkey (Türkiye)
Actively Recruiting
Research Team
D
Deniz Tuncer, PhD, PT
CONTACT
S
Serra Undil-Erdogmus, PT
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here