Actively Recruiting

Phase Not Applicable
Age: 20Years - 60Years
All Genders
NCT07414615

Aerobic Training in Lower Extremity Lymphedema

Led by Bezmialem Vakif University · Updated on 2026-02-19

24

Participants Needed

1

Research Sites

7 weeks

Total Duration

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AI-Summary

What this Trial Is About

This randomized controlled study aims to evaluate the effects of aerobic exercise training on gait, postural control, lower extremity muscle strength, and functional status in individuals with bilateral lower extremity lymphedema. A total of 24 participants aged between 20 and 60 years with a diagnosis of bilateral lower extremity lymphedema will be randomly assigned to either an aerobic exercise group or a control group. The aerobic exercise group will receive aerobic exercise training in addition to Complex Decongestive Therapy (CDT), while the control group will receive CDT alone. Lower extremity edema will be assessed using circumferential measurements taken from the ankle to the inguinal region. Gait function will be evaluated through angular and spatiotemporal analysis using Kinovea software, including parameters such as step length, walking speed, and double support time. Postural control will be assessed using the Balance Error Scoring System (BESS) and the Timed Up and Go Test. Lower extremity muscle strength and endurance will be evaluated using Manual Muscle Testing and the 30-Second Sit-to-Stand Test. Functional status of the lower extremities will be assessed using the Lower Extremity Functional Scale (LEFS).

CONDITIONS

Official Title

Aerobic Training in Lower Extremity Lymphedema

Who Can Participate

Age: 20Years - 60Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Aged between 20 and 60 years
  • Diagnosed with bilateral lower extremity lymphedema
  • Completed chemotherapy, radiotherapy, or other cancer treatments with no contraindications
  • Provided signed informed consent
  • Willing to participate in the study
Not Eligible

You will not qualify if you...

  • Uncontrolled heart or lung disease
  • Kidney failure
  • Musculoskeletal or neurological disorders affecting movement or balance
  • Infection in the lower leg
  • Unable to walk independently or requires walking aids
  • Pregnant
  • Visual, cognitive, or intellectual impairments interfering with study participation

AI-Screening

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Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Bezmialem Vakif University

Istanbul, Turkey (Türkiye)

Actively Recruiting

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Research Team

D

Deniz Tuncer, PhD, PT

CONTACT

S

Serra Undil-Erdogmus, PT

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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