Actively Recruiting
Aerobic Versus Leisure Group for Adolescents With Depression
Led by Lund University Hospital · Updated on 2025-03-26
122
Participants Needed
4
Research Sites
210 weeks
Total Duration
On this page
Sponsors
L
Lund University Hospital
Lead Sponsor
R
Region Halland
Collaborating Sponsor
AI-Summary
What this Trial Is About
The aim is to evaluate aerobic group exercise versus leisure group activities in adolescents with mild to moderate depression. Primary outcome is Children's Depression Rating Scale - Revised (CDRS-R). Secondary outcomes are Clinical Global Impressions - Severity and Improvement scales (CGI), self-reported Quick Inventory of Depression Symptomatology (QIDS- A17-SR), the self-reported Outcome Rating Scale (ORS), clinician rated Children Global Assessment Scale (C-GAS), aerobic capacity (VO2max), muscular strength, body, Body Mass Index (BMI), presence or activity of selected biological markers of neuroprotection and neuroinflammation in blood samples and a cost evaluation rated by parents with Trimbos/iMTA questionnaire for Costs associated with Psychiatric Illness - Child version (Tic-P) and the Child Health Utility (CHU9D) to facilitate estimation of Quality Adjusted Life Years. Further objectives are qualitative interviews to explore adolescents' experiences of the intervention as well as how their health and lifestyle are influenced and a validation of QIDS- A17-C and QIDS- A17-SR versus CDRS-R will be performed.
CONDITIONS
Official Title
Aerobic Versus Leisure Group for Adolescents With Depression
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Adolescents aged 13 to 17 years
- Diagnosed with mild to moderate depression according to DSM-5
- Have received evaluation and basic psychosocial interventions for 4-8 weeks (minimum three visits) without at least 50% improvement as recorded clinically
You will not qualify if you...
- Severe depression
- Eating disorder
- High risk for suicide
- Intellectual disability
- Engaged in physical activity in the last four weeks meeting recommended health levels (150 min/week moderate or 75 min/week high intensity)
- Adjusted antidepressant medication within the last four weeks or stimulants within the last two weeks
- Chronic physical illness preventing exercise
- Need for an interpreter
- Social circumstances that interfere with a regular exercise schedule
- Receiving psychotherapy
AI-Screening
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Trial Site Locations
Total: 4 locations
1
Region Halland
Halmstad, Sweden, 30290
Actively Recruiting
2
Prima Barn och vuxenpsykiatri AB (Stockholm-Handen)
Stockholm, Sweden, 11846
Actively Recruiting
3
PRIMA Barn och vuxenpsykiatri AB (Stockholm-Järva)
Stockholm, Sweden, 11846
Actively Recruiting
4
Region Halland
Varberg, Sweden, 43343
Actively Recruiting
Research Team
H
Håkan Jarbin, MD, PhD
CONTACT
R
Rebecca Mortazavi, MD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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