Actively Recruiting

Age: 18Years +
All Genders
NCT06319911

AETOS Shoulder System

Led by Smith & Nephew, Inc. · Updated on 2024-05-07

220

Participants Needed

5

Research Sites

338 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The goal of this study is to confirm the safety and performance of the AETOS Shoulder System for USA adoption. This is a prospective, open, adaptive, non-comparative, multi-centre investigation enrolling a maximum of 220 subjects in 2 cohorts (anatomic and reverse) at up to 15 sites. No intra-study comparator group will be included, and there will be no randomization

CONDITIONS

Official Title

AETOS Shoulder System

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Patients must be at least 18 years old and skeletally mature
  • Undergoing primary elective anatomic or reverse shoulder replacement surgery for rheumatoid arthritis, traumatic arthritis, non-inflammatory degenerative joint disease, or correction of functional deformity
  • Willing and able to complete all study procedures, visits, and post-operative therapy
  • Geographically stable and able to return for all follow-up visits
  • Informed of study risks and requirements and able to provide consent
Not Eligible

You will not qualify if you...

  • Contraindication to AETOS device
  • Undergoing revision shoulder replacement surgery
  • Indicated for hemiarthroplasty
  • Traumatic injury or fracture
  • Uncontrolled diabetes with hemoglobin A1C of 7.5 or greater
  • Conditions preventing proper healing or implant fixation
  • Poor bone quality or insufficient bone stock
  • Rapid joint destruction, marked bone loss, or osteomalacia
  • Muscular, neurologic, or vascular deficiencies affecting outcomes
  • Allergies to implant materials
  • Active infection, sepsis, or osteomyelitis
  • Abnormal blood test results unexplained by other disease
  • Non-functional deltoid or external rotator muscles for reverse arthroplasty
  • Significant injury to brachial plexus or axillary nerve paralysis for reverse arthroplasty
  • Uncooperative or neurologic disorder preventing study participation
  • Pregnant or planning pregnancy during follow-up
  • Body Mass Index over 35 kg/m2 or activities imposing high stress on implant
  • Known smoker, vaper, alcohol or drug abuser within 180 days
  • Previous participation and withdrawal from this trial
  • Participation in another device, drug trial, or competitive study

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 5 locations

1

California Pacific Orthopedics

San Francisco, California, United States, 94118

Actively Recruiting

2

Western Orthopaedics

Denver, Colorado, United States, 80210

Actively Recruiting

3

Hughston Foundation

Columbus, Georgia, United States, 31909

Actively Recruiting

4

Center for Orthopedics and Neurosurgical Care

Bend, Oregon, United States, 97701

Actively Recruiting

5

Rothman Institute

Philadelphia, Pennsylvania, United States, 19107

Actively Recruiting

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Research Team

T

Tammy Clark, MPH

CONTACT

K

Karlie Morgan

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

2

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