Investigating Stress-Induced Decision-Making Patterns in Adults With Borderline Personality Disorder Using Behavioral and Physiological Measures

What this Trial Is About

Researchers are investigating how personality traits and neuroendocrine systems influence decision-making in adults aged 18 to 45 years, focusing on individuals with Borderline Personality Disorder BPD and healthy controls. The study aims to understand the impact of neuroendocrine activity on decision-making patterns by examining stress responses and behavioral traits. Participants will take part in a one-time session that includes online behavioral tasks, a controlled stress induction called the Trier Social Stress Test involving public speaking and mental arithmetic, self-report surveys, and a cognitive assessment. Psychophysiological measures such as heart rate, blood flow, electrodermal activity, blood samples, and saliva will be collected during the session to assess nervous system activity. During the visit, researchers will monitor heart and nervous system functions using ECG, ICG, and EDA devices. They will measure goal-directed decision-making and bias toward social actions using the Social Decision Tree Task SDTT for about 40 minutes approximately two hours into the session. The study involves a single visit lasting around one hour and 35 minutes until the stress induction, with all data collected during this visit. Participation includes surveys, behavioral tasks, physiological monitoring, and biological sample collection.

Affect-based Impulsivity in Borderline Personality Disorder