Actively Recruiting

Phase 3
Age: 20Years +
All Genders
ID05766592

Affirmative Family and Individual Psychotherapy for Sexual and Gender Minority Adults and Their Nonaccepting Parents

Led by Yale University · Updated on 2026-01-13

124

Participants Needed

2

Research Sites

N/A

Total Duration

On this page

Sponsors

Y

Yale University

Lead Sponsor

B

Ben-Gurion University of the Negev

Collaborating Sponsor

AI-Summary

What this Trial Is About

Researchers are evaluating the effectiveness of two types of LGBTQ-affirmative psychotherapies delivered via telehealth for sexual and gender minority adults who have nonaccepting parents. The study focuses on adults living in New York, Pennsylvania, Connecticut, and Israel. It aims to see if these therapies reduce symptoms of depression and anxiety and to understand how specific factors like rejection sensitivity and parental acceptance affect mental health outcomes. Participants will be randomly assigned to receive either a 16-week course of individual LGBTQ-affirmative cognitive behavioral therapy (CBT) or 16 sessions of attachment-based family therapy (ABFT-SGM). The CBT sessions are delivered weekly and focus on addressing minority stress mechanisms, while the family therapy involves sessions with the adult child alone, with their parent(s), and with the parent(s) alone, aiming to improve the parent-child relationship regarding sexual orientation and gender identity. During the study, participants will complete assessments measuring depression, anxiety, suicidal thoughts, internalized stigma, emotion regulation, parental acceptance and rejection, and relationship quality at the start, immediately after treatment, and five months later. The researchers will monitor changes in these areas to evaluate treatment effects and mechanisms. The total duration of participation includes the 16-week therapy period plus follow-up assessments up to five months post-intervention.

CONDITIONS

Brief Title

Affirmative Family and Individual Psychotherapy for Sexual and Gender Minority Adults and Their Nonaccepting Parents

Who Can Participate

Age: 20Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Be 20 years old or older
  • Be fluent in English
  • Self-identify as lesbian, bisexual, queer, pansexual, or another non-heterosexual identity
  • Currently experience elevated depressive or anxiety symptoms
  • Report at least moderate parental rejection or low parental acceptance
  • Have at least one rejecting or nonaccepting parent willing to participate in therapy
  • Live in New York State, Pennsylvania, Connecticut, or Israel
Not Eligible

You will not qualify if you...

  • Receiving current mental health treatment one or more days per month, except medication management one day or less per week
  • Started a new medication within the past 30 days
  • Have active psychosis or mania
  • Have active suicidality or homicidality
  • Are legally mandated to attend treatment
  • Have gross cognitive impairment
  • Do not have a parent willing to participate

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

1 visit (in-person or remote)

Treatment

Duration - 16 weeks

Participants receive 16 weekly telehealth psychotherapy sessions of either LGBTQ-affirmative cognitive behavioral therapy or attachment-based family therapy with their nonaccepting parent(s).

16 weekly sessions via telehealth

Follow-up

Duration - 5 months

Participants complete assessments to measure changes in symptoms and psychosocial factors after treatment ends.

2 assessment visits (immediate post-intervention and 5-month post-intervention)

Trial Site Locations

Total: 2 locations

1

Yale LGBTQ Mental Health Initiative with the Yale School of Public Health Office

New York, New York, United States, 10001

Not Yet Recruiting

2

Ben-Gurion University Psychotherapy Research Lab

Beersheba, Israel, 84105

Actively Recruiting

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Research Team

J

John E Pachankis, PhD

D

Danielle M Chiaramonte, PhD

How is the study designed?

Study Type

INTERVENTIONAL

Masking

SINGLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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Published Research Related To This Trial

Revision and extension of a multidimensional measure of sexual minority identity: the Lesbian, Gay, and Bisexual Identity Scale.

Jonathan J Mohr, Matthew S Kendra

https://pubmed.ncbi.nlm.nih.gov/21319899

The Difficulties in Emotion Regulation Scale - Short Form (DERS-SF): psychometric properties and invariance between genders.

Patrícia Gouveia, Catarina Ramos, José Brito...

https://pubmed.ncbi.nlm.nih.gov/35522349

Measuring Adult Children's Perceptions of Their Parents' Acceptance and Rejection of Their Sexual Orientation: Initial Development of the Parental Acceptance and Rejection of Sexual Orientation Scale (PARSOS).

Ella Lubeznov Kibrik, Nitzan Cohen, Dana Stolowicz-Melman...

https://pubmed.ncbi.nlm.nih.gov/30142289

A construct validation study of the Response Styles Questionnaire Rumination Scale in participants with a recent-onset major depressive episode.

K L Kasch, D N Klein, M E Lara

https://pubmed.ncbi.nlm.nih.gov/11556274

The Experiences in Close Relationships-Relationship Structures questionnaire: a method for assessing attachment orientations across relationships.

R Chris Fraley, Marie E Heffernan, Amanda M Vicary...

https://pubmed.ncbi.nlm.nih.gov/21443364

Psychometric Properties of a Structured Diagnostic Interview for DSM-5 Anxiety, Mood, and Obsessive-Compulsive and Related Disorders.

David F Tolin, Christina Gilliam, Bethany M Wootton...

https://pubmed.ncbi.nlm.nih.gov/26988404

Abbreviated brief symptom inventory for use as an anxiety and depression screening instrument in primary care.

Ariel J Lang, Sonya B Norman, Adrienne Means-Christensen...

https://pubmed.ncbi.nlm.nih.gov/19016462