Psychometric Properties of a Structured Diagnostic Interview for DSM-5 Anxiety, Mood, and Obsessive-Compulsive and Related Disorders.
David F Tolin, Christina Gilliam, Bethany M Wootton...
https://pubmed.ncbi.nlm.nih.gov/26988404/Actively Recruiting
Led by Yale University · Updated on 2026-01-13
124
Participants Needed
2
Research Sites
N/A
Total Duration
Researchers are evaluating the effectiveness of two types of LGBTQ-affirmative psychotherapies delivered via telehealth for sexual and gender minority adults who have nonaccepting parents. The study focuses on adults living in New York, Pennsylvania, Connecticut, and Israel. It aims to see if these therapies reduce symptoms of depression and anxiety and to understand how specific factors like rejection sensitivity and parental acceptance affect mental health outcomes. Participants will be randomly assigned to receive either a 16-week course of individual LGBTQ-affirmative cognitive behavioral therapy CBT or 16 sessions of attachment-based family therapy ABFT-SGM. The CBT sessions are delivered weekly and focus on addressing minority stress mechanisms, while the family therapy involves sessions with the adult child alone, with their parents, and with the parents alone, aiming to improve the parent-child relationship regarding sexual orientation and gender identity. During the study, participants will complete assessments measuring depression, anxiety, suicidal thoughts, internalized stigma, emotion regulation, parental acceptance and rejection, and relationship quality at the start, immediately after treatment, and five months later. The researchers will monitor changes in these areas to evaluate treatment effects and mechanisms. The total duration of participation includes the 16-week therapy period plus follow-up assessments up to five months post-intervention.
CONDITIONS
Affirmative Family and Individual Psychotherapy for Sexual and Gender Minority Adults and Their Nonaccepting Parents
J
John E Pachankis, PhD
D
Danielle M Chiaramonte, PhD
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Yale University
Lead Sponsor
Ben-Gurion University of the Negev
Collaborating Sponsor
This table compares participation in this trial with other options available for this condition. The information is drawn from published research and the trial’s study details and is provided for educational purposes only.
| Factors | LGBTQ‑affirmative CBT | ABFT‑SGM | Standard LGBTQ‑affirmative psychotherapy |
|---|---|---|---|
| What it is | A structured 16‑session individual psychotherapy combining cognitive behavioral techniques with LGBTQ‑affirmative approaches delivered via telehealth. | A 16‑session attachment‑based family therapy delivered via telehealth with sexual and gender minority adults and their nonaccepting parent(s). | Affirmative psychotherapy integrating minority stress principles is recommended practice for LGBTQ individuals. |
| Role in trial | Participants are randomly assigned to receive this treatment. | Participants are randomly assigned to receive this family therapy. | This reflects usual psychotherapy available outside the trial rather than an assigned arm. |
| Primary use | To reduce depression and anxiety symptoms in SGM adults with nonaccepting parents via individual affirmative CBT. | To reduce depression and anxiety symptoms by improving parent‑child relations through family therapy. | To support mental health by affirming identity and addressing minority stress in adult LGBTQ individuals. |
| How it is given or performed | Delivered via telehealth in 16 weekly individual sessions. | Delivered via telehealth in 16 weekly family therapy sessions including the parent(s). | Typically delivered by trained therapists using LGBTQ‑affirmative principles in individual or group settings. |
| Evidence status | Efficacy is under investigation in this trial; prior research supports affirmative CBT’s feasibility and symptom reduction potential. | Efficacy is under investigation; prior pilot data suggest improvements in parental acceptance and attachment among SGM young adults and their parents. | Affirmative psychotherapy is broadly recommended and associated with improved mental health outcomes among LGBTQ clients. |
| Important limitations | Limited to SGM adults with at least one nonaccepting parent and elevated symptoms; results may not generalize beyond these criteria. | Requires parental engagement; not feasible if no parent willing to participate. | Broad recommendation lacks rigorous trial evidence for parental‑therapy integration in SGM adults; variability in delivery. |
Disclaimer: This comparison is created with the help of artificial intelligence(AI) and may contain errors or missing information. It is not medical advice and does not mean one option is better or safer than another. Clinical trials are still being studied, and joining a trial is your choice. Please consult your healthcare professional before making any decisions.
You may qualify if you...
You will not qualify if you...
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person or remote)
Duration - 16 weeks
Participants receive 16 weekly telehealth psychotherapy sessions of either LGBTQ-affirmative cognitive behavioral therapy or attachment-based family therapy with their nonaccepting parent(s).
16 weekly sessions via telehealth
Duration - 5 months
Participants complete assessments to measure changes in symptoms and psychosocial factors after treatment ends.
2 assessment visits (immediate post-intervention and 5-month post-intervention)
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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Lead Sponsor
Ben-Gurion University of the Negev
Collaborating Sponsor