Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
Healthy Volunteers
NCT05509166

Affirmative Psychotherapy for Sexual Minority Women's Mental and Behavioral Health

Led by Yale University · Updated on 2025-07-28

450

Participants Needed

1

Research Sites

234 weeks

Total Duration

On this page

Sponsors

Y

Yale University

Lead Sponsor

N

National Institute on Alcohol Abuse and Alcoholism (NIAAA)

Collaborating Sponsor

AI-Summary

What this Trial Is About

The purpose of this 2-arm randomized controlled trial is to assess the efficacy of a 10-session lesbian, gay, bisexual, transgender, and queer (LGBTQ)-affirmative cognitive-behavioral psychotherapy (CBT) delivered via telehealth in a large sample of sexual minority women (SMW) in New York, New Jersey and Pennsylvania. The investigators will assess whether the EQuIP (Empowering Queer Identities in Psychotherapy) treatment demonstrates significant reductions in heavy drinking (HD) and mental health symptoms (e.g., depression) compared to LGBTQ-affirmative treatment-as-usual.

CONDITIONS

Official Title

Affirmative Psychotherapy for Sexual Minority Women's Mental and Behavioral Health

Who Can Participate

Age: 18Years +
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Be 18 years of age or older
  • Be fluent in English
  • Self-identify as lesbian, bisexual, queer, pansexual, or other non-heterosexual identity
  • Report at least 8 standard drinks per week on average in the past 30 days, or at least 2 heavy drinking days (4 or more drinks in one day) in the past 30 days
  • Currently experience a DSM-5 depression or anxiety disorder, confirmed by diagnostic interview
  • Have at least minimum motivation to reduce drinking
  • Live in New York, New Jersey, or Pennsylvania and plan to stay for at least the next 4 months
Not Eligible

You will not qualify if you...

  • Currently receive mental health treatment at least one day per month
  • Have received any cognitive behavioral therapy in the past 3 months
  • Currently receive alcohol or drug abuse treatment (except mutual self-help like Alcoholics Anonymous)
  • Need alcohol detoxification as indicated by a score of 9 or higher on the Clinical Institute Withdrawal Assessment for Alcohol-Revised (CIWA-Ar)
  • Exhibit active psychosis or mania as assessed by clinical interview
  • Exhibit active suicidality or homicidality as assessed by clinical interview
  • Are legally mandated to attend treatment
  • Demonstrate gross cognitive impairment as assessed by the Telephone Interview for Cognitive Status

AI-Screening

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Trial Site Locations

Total: 1 location

1

Yale LGBTQ Mental Health Initiative with the Yale School of Public Office

New York, New York, United States, 10001

Actively Recruiting

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Research Team

J

John E Pachankis, PhD

CONTACT

D

Danielle M Chiaramonte, PhD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

DOUBLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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