Actively Recruiting
Age-related Changes in Retinal Oxygen Extraction in Healthy Subjects
Led by Medical University of Vienna · Updated on 2025-11-21
50
Participants Needed
1
Research Sites
69 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
It has been found that several systemic and ocular diseases are associated with impaired retinal oxygen extraction. In the present study, retinal oxygen extraction will be measured in different age groups in order to identify age related changes in otherwise healthy subjects. In addition, the study will explore short-term changes in retinal metabolism induced by breathing pure oxygen. Measurements will be performed with dynamic vessel analyzer and laser speckle flowgraphy to evaluate retinal blood flow and retinal oxygen saturation, in order to calculate retinal oxygen extraction.
CONDITIONS
Official Title
Age-related Changes in Retinal Oxygen Extraction in Healthy Subjects
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Men and women aged between 18 and 80 years
- Signed informed consent
- Normal eye exam results unless any abnormality is clinically irrelevant
- Normal medical history unless any abnormality is clinically irrelevant
- Nonsmokers
You will not qualify if you...
- Abuse of alcoholic beverages or drugs
- Participation in another clinical trial within the last 3 weeks
- Symptoms of a clinically relevant illness within 3 weeks before the study
- Blood donation in the 3 weeks before the study
- Pregnant or breastfeeding women
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Department of Clinical Pharmacology, Medical University of Vienna, Austria
Vienna, State of Vienna, Austria, 1090
Actively Recruiting
Research Team
D
Doreen Schmidl-Schordje, MD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
BASIC_SCIENCE
Number of Arms
1
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