Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
NCT07361445

Agilis RF TSP Early Feasibility Study

Led by Abbott Medical Devices · Updated on 2026-03-11

20

Participants Needed

2

Research Sites

24 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

This study is a prospective, acute, first-in-human, early feasibility study intended to assess the initial safety and performance of the Agilis™ Radiofrequency (RF) Transseptal (TSP) System in crossing the atrial septum for left atrial and left ventricular access during cardiac electrophysiology (EP) and interventional cardiology (IC) procedures. This study will be conducted in an acute setting. Subjects will be followed through hospital discharge, and no follow-up visits will be required for this study.

CONDITIONS

Official Title

Agilis RF TSP Early Feasibility Study

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Able and willing to provide written informed consent before any study procedure
  • Planning to undergo an ablation procedure in the left atrium, left ventricle, or a combined procedure with ablation and left atrial appendage occlusion device implantation requiring transseptal puncture
  • At least 18 years of age
  • Able and willing to follow all study requirements
Not Eligible

You will not qualify if you...

  • Currently participating in another clinical trial or participated in one within 30 days before screening without sponsor approval
  • Pregnant or nursing
  • Known intracardiac blood clot
  • Known circumferential pericardial effusion greater than 2 mm
  • Previous interatrial septal patch or prosthetic atrial septal defect closure device
  • Any thromboembolic event within the last 6 months
  • Known or suspected left atrial myxoma
  • Known or suspected myocardial infarction within the last 2 weeks
  • Unstable angina
  • Stroke or cerebral vascular accident within the last 3 months
  • Active infection
  • Unable to tolerate anticoagulation therapy
  • Other anatomical, medical, social, or psychological conditions that could limit participation or affect study results as judged by the investigator

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 2 locations

1

Arrhythmia Research Group (St. Bernards)

Jonesboro, Arkansas, United States, 72401

Actively Recruiting

2

California Pacific Medical Center -Van Ness Campus

San Francisco, California, United States, 94109

Actively Recruiting

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Research Team

B

Ben Gansemer, PhD

CONTACT

A

Amber Miller, PhD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

OTHER

Number of Arms

1

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