Actively Recruiting
Aging, Geriatric Syndromes and Clonal Hematopoiesis
Led by Washington University School of Medicine · Updated on 2026-05-12
2000
Participants Needed
1
Research Sites
737 weeks
Total Duration
On this page
Sponsors
W
Washington University School of Medicine
Lead Sponsor
E
Edward P. Evans Foundation
Collaborating Sponsor
AI-Summary
What this Trial Is About
In this study the investigators will incorporate a wide range of clinical variables associated with aging and cardiovascular disease to determine whether they are associated with mutation status independent of chronologic age. Clinically, aging can be operationalized using geriatric assessment, which entails a comprehensive multi-dimensional assessment of the health of an older adult, including measures of comorbidity, polypharmacy, functional status, cognition, depression, falls, social activities and social support. Given that aging is heterogeneous, geriatric assessment allows greater specificity for aging than chronological age alone.
CONDITIONS
Official Title
Aging, Geriatric Syndromes and Clonal Hematopoiesis
Who Can Participate
Eligibility Criteria
You may qualify if you...
- At least 50 years of age.
- Able to understand written and spoken English.
- Able to understand and willing to sign an IRB-approved written informed consent document or that of a legally authorized representative if applicable for the trauma cohort.
You will not qualify if you...
- Unable or unwilling to complete health questionnaire except for hip replacement participants.
- History of a recent acute viral illness within 30 days.
- Current cancer diagnosis with ongoing chemotherapy or radiation therapy.
- Current use of drugs causing DNA damage for non-cancer diseases.
- Vulnerable populations such as prisoners.
- Known infection with Hepatitis B or C, HTLV, or HIV.
- For optional bone marrow biopsy: use of blood thinning medications or allergy to lidocaine or other local anesthetics.
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
Washington University School of Medicine
St Louis, Missouri, United States, 63110
Actively Recruiting
Research Team
M
Meagan Jacoby, M.D.
CONTACT
K
Kristina Williams, B.S.
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
5
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