Actively Recruiting
Led by Arbeitsgemeinschaft medikamentoese Tumortherapie · Updated on 2025-04-10
500
Participants Needed
7
Research Sites
N/A
Total Duration
Metastatic colorectal cancer (mCRC) is a serious condition with limited treatment options after multiple therapies. Researchers are gathering detailed information on patients with mCRC who have already had at least two lines of systemic therapy. This registry aims to understand how these patients are treated and how they fare over time, collecting data from multiple cancer centers in Austria to better evaluate treatment patterns and outcomes. The study involves collecting existing medical data from patient charts, including treatment histories, test results, and imaging studies. Tumor tissue samples from deceased patients will be stored in a central biobank, and additional biological samples may be requested for specific research questions. No new diagnostic or treatment procedures are required beyond routine care. Data collection will continue until patient death or loss to follow-up. Participants' involvement includes providing consent for their routine medical data to be recorded in the registry. Researchers will monitor overall survival, progression-free survival, response rates, and potential predictive biomarkers over a period of up to 10 years. Patient confidentiality is maintained by assigning unique identifiers, and no extra visits or therapies are needed beyond usual care.
CONDITIONS
AGMT Metastatic Colorectal Cancer Registry (mCRC) Third Line and Beyond
You may qualify if you...
You will not qualify if you...
Complete this quick 3-step screening to check your eligibility
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person or remote) to obtain written consent and confirm eligibility
Duration - Up to 10 years or until patient death or loss to follow-up
Participants who undergo routine care are observed. Data from medical charts, imaging, and biomaterials are collected without additional interventions.
Data collection occurs as part of routine care visits; no additional visits required for the registry
Total: 7 locations
1
Ordensklinikum Linz, BHS - Interne I
Linz, Austria, 4010
Actively Recruiting
2
KUK Linz - Med Campus III.: Univ.-Klinik für Hämatologie und Internistische Onkologie
Linz, Austria, 4021
Actively Recruiting
3
LKH Feldkirch: Innere Medizin II/ Interne E (Hämatologie und Onkologie)
Rankweil, Austria, 6830
Actively Recruiting
4
Department of Internal Medicine III, Paracelsus Medical University Salzburg
Salzburg, Austria, 5020
Actively Recruiting
5
Klinikum Steyr: Innere Medizin II: Onkologie, Gastroenterologie, Angiologie
Steyr, Austria, 4400
Actively Recruiting
6
Klinikum Wels: Abteilung für Innere Medizin IV
Wels, Austria, 4600
Actively Recruiting
7
KH Zams: Innere Medizin Internistische Onkologie und Hämatologie
Zams, Austria, 6511
Actively Recruiting
D
Daniela Wolkersdorfer, Dr.
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
0
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Florian Huemer, Gudrun Piringer, Wolfgang Eisterer...
https://pubmed.ncbi.nlm.nih.gov/41860053