Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
Healthy Volunteers
NCT06632886

AI-Assisted Non-Contrast CT for Multi-Cancer Screening

Led by Guo ShiWei · Updated on 2024-10-09

1000000

Participants Needed

1

Research Sites

156 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Cancer poses a major public health challenge in China. Early detection can improve treatment outcomes and survival rates. In this study, we will conduct a large-scale, prospective, multi-center cohort study to evaluate the utility of AI-assisted non-contrast CT for multi-cancer screening. The study aims to enroll 1 million asymptomatic participants undergoing routine health examinations, using an AI imaging model based on non-contrast CT to detect seven cancers such as lung, liver, gastric, colorectal, esophageal, pancreatic, and breast cancers. Positive cases will be required to be referred to Shanghai Changhai Hospital for further imaging and care based on National Comprehensive Cancer Network (NCCN) and American College of Radiology (ACR) guidelines. The goal is to assess the AI model's diagnostic performance for seven cancer types, especially for early-stage, resectable tumors.

CONDITIONS

Official Title

AI-Assisted Non-Contrast CT for Multi-Cancer Screening

Who Can Participate

Age: 18Years +
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Able and willing to provide informed consent
  • Has undergone an abdominal or chest non-contrast CT scan
Not Eligible

You will not qualify if you...

  • Diagnosed with lung, liver, stomach, colon, esophageal, pancreatic, or breast cancer within the last five years
  • Has any medical condition that contraindicates high-resolution MRI, CT with contrast, or endoscopy
  • Cannot be followed up or is participating in other clinical trials

AI-Screening

AI-Powered Screening

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Trial Site Locations

Total: 1 location

1

Changhai Hospital

Shanghai, Shanghai Municipality, China, 200433

Actively Recruiting

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Research Team

W

Wang Beilei, M.D.

CONTACT

G

Guo Shiwei, M.D.

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

DIAGNOSTIC

Number of Arms

1

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