Actively Recruiting

Age: 15Years - 45Years
All Genders
NCT06511713

AI-Assisted Rapid Warning for Mental Disorders Based on High-Resolution Fundus Imaging and High-Speed Eye-Tracking

Led by Shanghai Mental Health Center · Updated on 2024-07-23

2000

Participants Needed

1

Research Sites

75 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

This project aims to collect eye-tracking trajectories and fundus imaging data from individuals seeking mental health services. By utilizing artificial intelligence, combining dynamic (eye-tracking) and static (fundus) data, and employing convolutional neural network analysis methods, the investigators will develop models for the classification and early warning of common mental disorders. These models will assist clinicians in making objective diagnoses of common mental disorders and in predicting the risk of adverse outcomes, thereby addressing the significant technical bottleneck of the current lack of objective diagnostic and warning instruments for mental disorders.

CONDITIONS

Official Title

AI-Assisted Rapid Warning for Mental Disorders Based on High-Resolution Fundus Imaging and High-Speed Eye-Tracking

Who Can Participate

Age: 15Years - 45Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Be aged 14 to 45 years old
  • Have completed at least 6 years of primary education
  • Be drug-naïve (no prior psychiatric medication use)
  • Understand the survey, be willing to enroll, and sign informed consent
  • Meet Criteria of Prodromal Syndrome via Structured Interview for Prodromal Syndromes/Scale of Prodromal Symptoms (SIPS/SOPS) with at least one prodromal syndrome: brief intermittent psychotic syndrome, attenuated positive symptom syndrome, or genetic risk and deterioration syndrome
  • Meet ICD-11 diagnostic criteria for schizophrenia
  • Meet ICD-11 diagnostic criteria for mood disorders
  • Meet ICD-11 diagnostic criteria for anxiety disorders
  • Meet ICD-11 diagnostic criteria for neurocognitive disorders
Not Eligible

You will not qualify if you...

  • Have acute or chronic renal failure, liver cirrhosis, or active liver diseases
  • Have abnormal laboratory test results considered clinically significant by researchers
  • Have severe or unstable physical diseases such as neurological disorders (delirium, dementia, stroke, epilepsy, migraine, etc.), congestive heart failure, angina pectoris, myocardial infarction, arrhythmia, untreated or uncontrolled hypertension, malignant tumors, immune compromise, or blood glucose above 12 mmol/L
  • Have alcohol abuse within 30 days or alcohol/drug dependence within 6 months before the trial
  • Are pregnant, lactating, or a woman of childbearing age who tests positive for urine human chorionic gonadotropin, or men and women not using effective contraception or planning pregnancy within 3 months after the trial starts
  • Had a stroke within the last month
  • Are participating in another clinical trial within 30 days before baseline
  • Are judged by investigators as unsuitable for the clinical trial

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Shanghai Mental Health Center

Shanghai, Shanghai Municipality, China, 200030

Actively Recruiting

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Research Team

T

TianHong Zhang, Doctor

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

2

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AI-Assisted Rapid Warning for Mental Disorders Based on High-Resolution Fundus Imaging and High-Speed Eye-Tracking | DecenTrialz