Actively Recruiting

Age: 20Years - 43Years
FEMALE
NCT07473739

AI-Based Ultrasound Prediction of Pregnancy Outcomes in Placental-Related Fetal Growth Restriction (MVM-FGR): A Prospective Cohort Study

Led by Xinhua Hospital, Shanghai Jiao Tong University School of Medicine · Updated on 2026-03-16

300

Participants Needed

1

Research Sites

308 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The goal of this prospective cohort study is to enroll pregnancies complicated by placental-related fetal growth restriction (FGR) and to develop predictive models for adverse short- and long-term outcomes. This will be achieved by collecting novel intrauterine monitoring indicators along the fetal brain-placenta-heart axis, combined with conventional fetal surveillance parameters, in order to improve risk stratification and guide clinical management, ultimately improving pregnancy outcomes. The study will include pregnant women with singleton pregnancies complicated by isolated early-onset placental insufficiency-related FGR, preferably those with abnormal umbilical artery Doppler findings, who elect to continue the pregnancy. The main question it aims to answer is: • Whether a predictive model integrating novel intrauterine monitoring indicators along the fetal brain-placenta-heart axis with conventional monitoring parameters can accurately predict perinatal and neonatal adverse outcomes in pregnancies complicated by placental-related FGR.

CONDITIONS

Official Title

AI-Based Ultrasound Prediction of Pregnancy Outcomes in Placental-Related Fetal Growth Restriction (MVM-FGR): A Prospective Cohort Study

Who Can Participate

Age: 20Years - 43Years
FEMALE

Eligibility Criteria

Eligible

You may qualify if you...

  • Singleton pregnancy
  • Isolated early-onset placental insufficiency-related fetal growth restriction (FGR), preferably with abnormal umbilical artery Doppler findings
  • Pregnancy managed expectantly with continuation of pregnancy
Not Eligible

You will not qualify if you...

  • Multiple pregnancy complicated by selective fetal growth restriction (sFGR)
  • FGR caused by fetal structural anomalies, genetic abnormalities, or intrauterine infection
  • Twin pregnancy with intrauterine fetal demise (IUFD) of one fetus

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Xinhua Hospital Affiliated to Shanghai Jiaotong University School of Medicine Shanghai, Shanghai, China

Shanghai, China, 200092

Actively Recruiting

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Research Team

L

Luming Sun, Prof

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

1

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AI-Based Ultrasound Prediction of Pregnancy Outcomes in Placental-Related Fetal Growth Restriction (MVM-FGR): A Prospective Cohort Study | DecenTrialz