Actively Recruiting

Phase Not Applicable
Age: 20Years - 99Years
All Genders
NCT07226934

An AI-Generated, Personalized Question Prompt List Intervention for Patients With Hematologic Cancers

Led by Washington University School of Medicine · Updated on 2026-03-25

40

Participants Needed

1

Research Sites

17 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The goal of this study is to evaluate the feasibility and preliminary efficacy of an artificial intelligence (AI)-generated personalized question prompt list (a list of suggested questions to ask during outpatient appointments) for patients with hematologic cancers. The intervention will involve tailoring a standardized prompt to patients' individual characteristics and concerns. This prompt will then be used to ask Washington University's (WashU) HIPAA compliant ChatGPT to generate personalized question lists for outpatient appointments. Analyses will assess the impact of personalized QPLs on patients' question-asking behavior; communicative self-efficacy; and self-reported amount and satisfaction with information obtained about their disease and its treatment. Sub-analyses will explore patterns in questions generated by WashU ChatGPT. Patients will also provide feedback pertaining to the perceived helpfulness and ease-of-use of WashU-ChatGPT-generated question lists, as well as their attitudes and intentions regarding use of AI chatbots and whether they would engage in pre-appointment AI-assisted question brainstorming independently in the future.

CONDITIONS

Official Title

An AI-Generated, Personalized Question Prompt List Intervention for Patients With Hematologic Cancers

Who Can Participate

Age: 20Years - 99Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Diagnosed with lymphoma (ICD-10 codes C81-C88) or multiple myeloma (ICD codes C90.0-C90.02)
  • Scheduled follow-up appointment at a participating outpatient oncology clinic within the next month
  • Receiving infusion or injection-based systemic therapy intended to cure or manage the disease at a frequency of once every 1-4 weeks
  • Aged between 20 and 99 years at enrollment
  • Able to independently consent to medical care without cognitive impairment
  • No visual impairments or English literacy limitations interfering with study participation
  • Able to use email and complete electronic informed consent
Not Eligible

You will not qualify if you...

  • Patients aged under 20 or over 99 years
  • Documented cognitive impairment or need for legally authorized representative to consent
  • Visual impairments or English literacy issues that prevent reading or communicating during appointments
  • Unable to use email or complete electronic consent forms

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Washington University School of Medicine

St Louis, Missouri, United States, 63110

Actively Recruiting

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Research Team

J

Jessica Hahne, MA, MPH

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

HEALTH_SERVICES_RESEARCH

Number of Arms

1

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