Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
NCT07206602

AI-Guided Left Bundle Branch Area Pacing

Led by Mayo Clinic · Updated on 2026-02-18

224

Participants Needed

1

Research Sites

92 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The purpose of this study is to compare the effectiveness of AI-guided LBBAP versus conventional LBBAP (not AI-guided) in improving CRT response rates and clinical outcomes.

CONDITIONS

Official Title

AI-Guided Left Bundle Branch Area Pacing

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Age 18 years or older
  • Left Ventricular Ejection Fraction (LVEF) less than 50% within 6 months before enrollment
  • Resting QRS duration 130 milliseconds or more on ECG OR anticipated right ventricular pacing over 40% OR device in place with right ventricular pacing over 40% within 6 months before enrollment
  • Optimized on guideline-directed medical therapy for heart failure
  • AI-ECG probability of low LVEF greater than 0.5
Not Eligible

You will not qualify if you...

  • Age less than 18 years
  • Unable to participate in follow-up visits
  • Pregnancy

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Mayo Clinic in Rochester

Rochester, Minnesota, United States, 55905

Actively Recruiting

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Research Team

J

Joseph Abdel Messih

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

DOUBLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

OTHER

Number of Arms

2

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