Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
ID07522944

Artificial Intelligence-Guided Relaxation Interventions for Reducing Anxiety and Enhancing Coping Strategies in Patients Undergoing Hemodialysis

Led by Alexandria University · Updated on 2026-05-12

60

Participants Needed

2

Research Sites

1 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Researchers are investigating whether an artificial intelligence (AI)-guided relaxation program can help reduce anxiety and improve coping skills in adults undergoing maintenance hemodialysis. This study focuses on patients with end-stage renal disease who often experience significant stress and discomfort during dialysis. The trial uses a randomized controlled design to compare patient well-being before and after using the AI intervention against standard care. Sixty adult patients will be randomly assigned to one of two groups: an intervention group receiving AI-driven relaxation sessions during their dialysis treatments, and a control group receiving routine nursing care without AI. The AI program offers personalized relaxation techniques like deep breathing, progressive muscle relaxation, guided imagery, and mindfulness through a digital platform with headphones. These sessions last 20 to 30 minutes, occurring two to three times weekly over four to six weeks. Participants will be assessed before and after the intervention using standardized questionnaires measuring anxiety, depression, coping strategies, and perceived relaxation. The study also includes interviews with participants in the intervention group to explore their experiences with the AI technology. Data collection aligns with the 4-6 week treatment period, aiming to understand both quantitative changes and personal impacts. Safety and adherence are monitored throughout the study.

CONDITIONS

Brief Title

AI-Guided Relaxation for Hemodialysis Anxiety

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Adult patients aged 18 years or older
  • Confirmed diagnosis of end-stage renal disease (ESRD) receiving maintenance hemodialysis for at least 3 months
  • Conscious, oriented, and able to communicate effectively
  • Documented mild-to-moderate anxiety confirmed by GAD-7 or HADS screening
  • Adequate visual and auditory function to use the AI-guided relaxation platform
  • Willing to participate and provide written informed consent prior to enrollment
Not Eligible

You will not qualify if you...

  • History of epilepsy, chronic vertigo, or seizure disorders
  • Severe cognitive impairment or diagnosed psychiatric disorders such as dementia or schizophrenia
  • Acute medical complications or hemodynamic instability during dialysis
  • Severe visual impairment or blindness preventing use of the digital relaxation device
  • Skin infections or injuries on the face or head that interfere with using a headset
  • Currently enrolled in any other psychological or relaxation intervention study

AI-Screening

AI-Powered Screening

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Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

1 visit (in-person)

Implementation

Duration - 4 to 6 weeks

Participants in the intervention group receive AI-guided relaxation sessions during their routine hemodialysis treatments to help manage anxiety and enhance coping strategies. Sessions last approximately 20-30 minutes and are delivered two to three times per week over four to six weeks using a tablet or mobile device with headphones. Participants in the control group undergo standard hemodialysis nursing care without the AI intervention.

2 to 3 sessions per week during routine dialysis

Trial Site Locations

Total: 2 locations

1

Faculty of Nursing, Alexandria University

Alexandria, Alexandria Governorate, Egypt, 21511

Actively Recruiting

2

Faculty of Nursing, Alexandria University

Alexandria, Alexandria Governorate, Egypt, 2500

Not Yet Recruiting

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Research Team

M

Mohamed Fakhry Ahmed Salem Dr, PhD

How is the study designed?

Study Type

INTERVENTIONAL

Masking

SINGLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

SUPPORTIVE_CARE

Number of Arms

2

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