Actively Recruiting
AI & Radiomics for Stratification of Lung Nodules After Radically Treated Cancer
Led by Royal Marsden NHS Foundation Trust · Updated on 2022-05-24
1000
Participants Needed
2
Research Sites
263 weeks
Total Duration
On this page
Sponsors
R
Royal Marsden NHS Foundation Trust
Lead Sponsor
I
Institute of Cancer Research, United Kingdom
Collaborating Sponsor
AI-Summary
What this Trial Is About
This study will assess the utility of radiomics and artificial intelligence approaches to new lung nodules in patients who have undergone radical treatment for a previous cancer.
CONDITIONS
Official Title
AI & Radiomics for Stratification of Lung Nodules After Radically Treated Cancer
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Confirmed history of previous radically or curative-intent treated solid organ cancer within 10 years of new CT thoracic scan showing a new pulmonary nodule
- Biopsy confirming previous malignancy with multidisciplinary team (MDT) consensus and successful remission after treatment, or MDT consensus confirming cancer and decision to treat with subsequent remission if biopsy not possible
- Radical treatment for previous cancer defined as surgical resection, radical radiotherapy or stereotactic beam radiotherapy, radical chemotherapy, radical chemo-radiotherapy, or multi-modality treatment including any of these
- New pulmonary nodule ground truth known by either 2-year stable or resolved scan data for benign disease, or progressive enlargement or number increase with MDT consensus determining metastatic disease or new primary malignancy
- Biopsy confirmation of benign disease or malignancy where applicable
- CT scan slice thickness 2.5mm or less
- Nodule size 5mm or larger
You will not qualify if you...
- CT imaging older than 10 years
- Non-solid hematological malignancies including leukemia
- Cases of radically treated primary cancer with early oligometastatic recurrence treated radically
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 2 locations
1
The Royal Marsden NHS Foundation Trust (Chelsea Site)
London, United Kingdom, SW3 6JJ
Actively Recruiting
2
Royal Brompton Hospital
London, United Kingdom, SW3 6NP
Actively Recruiting
Research Team
S
Sejal Jain
CONTACT
L
Laura Boddy
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
3
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