Actively Recruiting

Phase Not Applicable
Age: 0 - 1Day
All Genders
ID03919188

Comparison of Air vs. Cutaneous Control Mode for Preterm Infants 64 32 Weeks Gestation in Closed Incubators: Impact on Body Growth and Morbidity

Led by Centre Hospitalier Universitaire, Amiens · Updated on 2025-05-29

164

Participants Needed

1

Research Sites

N/A

Total Duration

On this page

Sponsors

C

Centre Hospitalier Universitaire, Amiens

Lead Sponsor

U

University Hospital, Rouen

Collaborating Sponsor

AI-Summary

What this Trial Is About

Researchers are studying preterm infants born between 25 and 32 weeks of gestation to compare two methods of incubator temperature control and their effects on infant weight growth and health. The study is based on earlier findings that lower body temperature on admission relates to higher illness and death rates in preterm infants. It aims to see if using a new software to calculate personalized air temperature in incubators can improve growth and reduce side effects compared to the traditional skin temperature control method. The study compares two incubator control methods: air temperature control (ATC), which uses software to set air temperature to reduce body heat loss to zero, and skin servocontrol (SSC), which adjusts incubator temperature based on the infant's skin temperature. Both methods are evaluated in closed incubators for preterm infants. The trial randomly assigns infants to one of these two methods to study their effects during the first 10 days of life. Participants will be monitored for changes in body weight until day 10, along with comfort, thermal stress, and humidity challenges. The study also tracks neonatal illness occurrences up to 40 weeks of amenorrhea and length of hospital stay until discharge or 40 weeks of amenorrhea. Parents provide written consent, and infants are included within the first day of life. The study continues through hospitalization, assessing health outcomes and safety related to the incubator settings.

CONDITIONS

Brief Title

Air vs. Cutaneous Control Mode for Preterm Infants ≤ 32 WG in Incubators: Impact on Body Growth and Morbidity

Who Can Participate

Age: 0 - 1Day
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Preterm infant born between 25+0 and 32+0 weeks of gestation
  • Preterm infant included in the study before 24 +/- 12 hours of life
  • Preterm infant nursed in a closed incubator
  • Written informed consent from parents
Not Eligible

You will not qualify if you...

  • Newborn infant with polymalformative syndrome
  • Life threatening events or serious heart disease

AI-Screening

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Your Study Journey

Screening

Duration - Up to 24 hours after birth

Participants are screened for eligibility to participate in the trial.

1 visit (in-person)

Treatment

Duration - Until day 10 of life

Participants receive incubator care using either air temperature control (ATC) or skin servocontrol (SSC) methods.

Daily in-person visits for up to 10 days

Follow-up

Duration - Until 40 weeks of amenorrhea or end of hospitalization

Participants are monitored for neonatal morbidity and length of hospitalization until reaching 40 weeks of amenorrhea or discharge.

Regular visits until discharge or 40 weeks of amenorrhea

Trial Site Locations

Total: 1 location

1

Amiens University Hospital

Amiens, Picardie, France, 80054

Actively Recruiting

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Research Team

P

Pierre Tourneux, Pr

M

Momar Diouf, Dr

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

OTHER

Number of Arms

2

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