Actively Recruiting
Air-polishing With Erythritol During Orthodontic Tretament
Led by Catherine Giannopoulou · Updated on 2026-05-05
60
Participants Needed
1
Research Sites
259 weeks
Total Duration
On this page
Sponsors
C
Catherine Giannopoulou
Lead Sponsor
U
University of Geneva, Switzerland
Collaborating Sponsor
AI-Summary
What this Trial Is About
Patients with multi-bracketed fixed orthodontic treatment are at increased risk of developing white spot lesions (WSL) and gingivitis. Various preventive strategies have been examined to prevent the development of WSLs. During initial non-surgical periodontal therapy, the use of subgingival air-polishing with erythritol powder has shown promising results in reducing deep pockets and gingival inflammation. The efficacy of its use as monotherapy in preventing WSLs and gingival inflammation in patients during orthodontic treatment, has not yet been tested. The primary objective of the present study is to compare the effectiveness of an air-polishing device used as monotherapy versus ultrasonic instrumentation (the current gold standard procedure) in preventing white spot lesions (WSL) and gingivitis among young patients undergoing multi-bracketed fixed orthodontic treatment.
CONDITIONS
Official Title
Air-polishing With Erythritol During Orthodontic Tretament
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Subjects about to undergo fixed orthodontic treatment will be invited to participate.
- Age between 12 and 16 years only participants
- Informed written consent obtained by the parents
You will not qualify if you...
- Clinically significant concomitant disease states such as renal failure, hepatic dysfunction, cardiovascular disease, etc.
- Known or suspected non-compliance, drug or alcohol abuse
- Inability to follow the procedures of the investigation due to language problems, psychological disorders, dementia, etc.
- Participation in another investigation with an investigational drug or medical device within 30 days before or during this study
- Previous enrolment into the current investigation
- Enrolment of the principal investigator, their family members, employees, or dependent persons
- History of fixed orthodontic treatment
- Defects on enamel on labial surfaces of the teeth
- Untreated cavitated lesions
- Plaque levels greater than 25%
- Periodontitis
- Multiple missing teeth
- Cleft lip and/or palate or other craniofacial anomalies or syndromes
- Patients taking any regular medication
- Patients with asthmatic problems
AI-Screening
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Trial Site Locations
Total: 1 location
1
University of Geneva, University Clinics of Dental Medicine
Geneva, Canton of Geneva, Switzerland, 1205
Actively Recruiting
How is the study designed?
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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