Actively Recruiting

Age: 18Years - 65Years
All Genders
NCT06259760

AKI Risk Factors Analysis After Intentional Hypotensive Anesthesia

Led by Kaohsiung Medical University Chung-Ho Memorial Hospital · Updated on 2024-02-14

50

Participants Needed

1

Research Sites

147 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

This project investigates intentionally hypotensive management such as NTG (nitroglycerin) or NTG+Trandate during general anesthesia in patients undergoing orthognathic surgery. Throughout the entire surgical procedure, blood biochemical and urine monitoring will be conducted. Serum creatinine (Cr) levels, urine analysis, and perioperative monitoring will be utilized as indicators for assessing renal function during the surgery. The objective is to assess its potential renal injury and identify early risk factors for acute kidney injury (AKI). Timely recognition of these factors will allow for the implementation of appropriate intervention strategies, aiding in the prevention of postoperative acute kidney injury. This approach contributes to achieving the goals of Enhanced Recovery After Surgery (ERAS) for surgical patients, promoting faster postoperative recovery.

CONDITIONS

Official Title

AKI Risk Factors Analysis After Intentional Hypotensive Anesthesia

Who Can Participate

Age: 18Years - 65Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Patients classified as American Society Anesthesiologist class I to II undergoing oro-maxillo-facial surgery
  • Unlimited mouth opening
Not Eligible

You will not qualify if you...

  • Arthritis causing limited mouth opening
  • Persistent liver dysfunction
  • Chronic renal insufficiency
  • Body mass index of 35 kg/m2 or higher
  • Past or family history of malignant hyperthermia
  • Diabetes treated with insulin
  • Uncontrolled essential hypertension

AI-Screening

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Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Kaohsiung Medical University Chung-Ho Memorial Hospital

Kaohsiung City, Sanmin Dist, Taiwan, 80756

Actively Recruiting

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Research Team

K

Kuang-I Cheng, Phd

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

0

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