Improving Care for Preterm Infants Born at 32 to 36 Weeks in Alberta NICUs Using Collaborative Quality Improvement
Led by University of Calgary · Updated on 2025-07-18
9500
Participants Needed
12
Research Sites
N/A
Total Duration
AI-Summary
What this Trial Is About
The trial focuses on moderate and late preterm infants born between 32 and 36 weeks gestation who are admitted to Level 2 and 3 Neonatal Intensive Care Units NICUs across Alberta. Researchers aim to find out if applying collaborative quality improvement methods and standardized care bundles can reduce the length of hospital stays and help babies get home faster. This stepped-wedge cluster randomized trial includes 12 NICUs randomized to adopt the intervention at different times, allowing comparison against current standard care.
The intervention involves multiple collaborative quality improvement strategies building dedicated QI teams in each NICU, providing standardized QI education, implementing two care bundles focused on respiratory and nutritional support, mentoring by experienced QI members, and facilitating collaborative networking with regular virtual and in-person meetings. Participating NICUs will transition from current practices to this intervention in phases over three years. During the control period, NICUs continue their usual care and any ongoing QI activities without the new intervention strategies.
Participants progress will be monitored from birth until discharge or death, with assessments continuing up to six months after their due date. Researchers will track hospital stay length, healthcare costs, respiratory support duration, feeding milestones, growth measurements, rehospitalizations, mortality, and staff perceptions of QI implementation. Data will be collected through clinical records and surveys. The study spans from May 2023 to August 2027, aiming to improve care quality and outcomes for these preterm infants.
CONDITIONS
Brief Title
Alberta Collaborative QI Strategies to Improve Outcomes of Moderate and Late Preterm Infants (ABC-QI Trial)
Research Team
M
Mahesha Bandara, MSc
A
Ayman Abou Mehrem, MD
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Admitted to participating Level 2 or Level 3 NICUs or postpartum units
NICU management staff, nurses, nurse practitioners, physicians, and allied health staff may participate in surveys and interviews
You will not qualify if you...
Infants with major congenital anomalies or chromosomal abnormalities
Primary admission to a surgical NICU at specified hospitals
Infants born in or transferred to NICUs outside Alberta
Patients with confidentiality restrictions on accessing health records
Your Study Journey
Screening
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Control Arm - Current management
Duration - Approximately 1 year prior to transitioning to intervention
Participants in NICUs will receive current standard care practices and may participate in quality improvement activities relevant to their unit but without the study interventions until their unit transitions to the intervention arm.
Ongoing clinical care and observations as part of routine NICU management
Intervention Arm - Collaborative Quality Implementation Strategies
Duration - Up to 3 years depending on NICU transition timing
Participants in NICUs receive a set of collaborative quality improvement strategies including team building, education, implementation of standardized respiratory and nutritional care bundles, mentoring, and collaborative networking to improve care practices.
Ongoing clinical care and observations as part of routine NICU management
Follow-up
Duration - Up to 6 months after birth due date
Participants are followed until they reach a corrected age of 6 months to assess outcomes such as length of stay, growth, rehospitalizations, and mortality.
Follow-up visits or record reviews occurring periodically until 6 months corrected age
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
SEQUENTIAL
Primary Purpose
HEALTH_SERVICES_RESEARCH
Number of Arms
2
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Published Research Related To This Trial
Alberta Collaborative Quality Improvement Strategies to Improve Outcomes of Moderate and Late Preterm Infants (ABC-QI) Trial: a protocol for a multicentre, stepped-wedge cluster randomized trial.