Actively Recruiting
Albumin-bound Paclitaxel and Carboplatin Versus Epirubicin and Docetaxel for Triple-negative Breast Cancer
Led by Shengjing Hospital · Updated on 2021-07-20
110
Participants Needed
7
Research Sites
280 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
To investigate the efficacy of albumin-bound paclitaxel combined with carboplatin versus epirubicin combined with docetaxel as neoadjuvant therapy for triple-negative breast cancer.
CONDITIONS
Official Title
Albumin-bound Paclitaxel and Carboplatin Versus Epirubicin and Docetaxel for Triple-negative Breast Cancer
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Breast cancer confirmed by X-ray with tumor stage II-III and negative for estrogen receptor, progesterone receptor, and HER2
- Estimated survival longer than 3 months
- Presence of clinically measurable lesions
- Karnofsky functional status score of 70 or higher
- Normal blood tests, liver and kidney function, and near normal electrocardiogram
- Age between 18 and 70 years
You will not qualify if you...
- Stage IV breast cancer with bone or other distant metastasis
- Severe kidney failure
- Serious heart or lung diseases making chemotherapy intolerable
- Previous antineoplastic therapy
- Failure of 2 cycles of neoadjuvant chemotherapy with change or termination of treatment
- History of other cancers
- Severe organ dysfunction or poor health unable to tolerate chemotherapy
- Mental or nervous system disorders preventing treatment compliance
- Allergy to dexamethasone or chemotherapy drugs
- Pregnant or breastfeeding women
- Participation in other clinical trials
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 7 locations
1
Cancer Hospital Affiliated to Harbin Medical University
Harbin, Heilongjiang, China, 150081
Actively Recruiting
2
The Second Hospital of Jilin University
Changchun, Jilin, China, 130041
Actively Recruiting
3
Dalian Municipal Central Hospital
Dalian, Liaoning, China, 116033
Actively Recruiting
4
Panjin Liaohe Oilfield Gem Flower Hospital
Panjin, Liaoning, China, 124010
Actively Recruiting
5
Shengjing Hospital of China Medical University
Shenyang, Liaoning, China, 110004
Actively Recruiting
6
The Fourth Affiliated Hospital of China Medical University
Shenyang, Liaoning, China, 110032
Actively Recruiting
7
Liaoning Cancer Hospital & Institute
Shenyang, Liaoning, China, 110042
Actively Recruiting
Research Team
X
Xi Gu, M.D.
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
TRIPLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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