Actively Recruiting

Age: 18Years - 80Years
All Genders
ID04264065

Albumin and Prognosis of Severely Burned Patients Observational Study for the BurnICU Group of ESICM

Led by Assistance Publique - Hôpitaux de Paris · Updated on 2026-01-15

200

Participants Needed

1

Research Sites

N/A

Total Duration

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AI-Summary

What this Trial Is About

Researchers are studying the outcomes of adults with severe burns covering more than 30% of their total body surface area. The study focuses on how albumin administration during the first 24 hours of burn resuscitation may impact prognosis, including risks like organ failure and mortality. This observational study aims to collect detailed data on patient outcomes to help design future interventional trials evaluating albumin's role in burn care. Participants are adults aged 18 to 80 years admitted to intensive care units within 12 hours of severe burns. The study observes current management practices, including how albumin is given, such as dose, duration, and method of administration. The research follows patients for 90 days after admission to track their health and treatments. During the study, researchers will monitor combined outcomes of death, severe acute kidney failure, and serious respiratory distress within 28 days after the burn injury. They will also assess rates of kidney failure, respiratory distress, abdominal complications, sepsis, and organ function scores up to 90 days post-injury. This thorough follow-up helps understand how albumin use relates to recovery and complications in severe burn patients.

CONDITIONS

Brief Title

Albumin and Prognosis of Severely Patients Burns

Who Can Participate

Age: 18Years - 80Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Patients over 18 years of age
  • Burns covering more than 30% of total body surface area
  • Patients admitted to intensive care unit within 12 hours of burn injury
Not Eligible

You will not qualify if you...

  • Pregnancy
  • Patients with limitation of active treatments on admission to burn ICU
  • Pre-hospital cardiac arrest
  • Moribund patients including pre-hospital cardiac arrest or burns covering more than 95% of body surface
  • Age over 80 years

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Your Study Journey

Screening

Duration - Up to 12 hours after burn injury

Participants are screened for eligibility to participate in the trial.

Monitoring

Duration - 90 days after admission

Participants with severe burns are observed and data are collected on their clinical status, including kidney function, respiratory status, and other complications.

Data collection at multiple time points, including Days 1 to 7, Day 28, and Day 90

Trial Site Locations

Total: 1 location

1

Hopital saint Louis

Paris, France, France, 75010

Actively Recruiting

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Research Team

F

François Dr DEPRET, MD

M

Matthieu Pr LEGRAND, MD-PhD

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

0

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Published Research Related To This Trial

Hold the Pendulum: Rates of Acute Kidney Injury are Increased in Patients Who Receive Resuscitation Volumes Less than Predicted by the Parkland Equation.

Stephanie A Mason, Avery B Nathens, Celeste C Finnerty...

https://pubmed.ncbi.nlm.nih.gov/27828823

Five percent albumin for adult burn shock resuscitation: lack of effect on daily multiple organ dysfunction score.

Andrew B Cooper, Stephen M Cohn, Haibo S Zhang...

https://pubmed.ncbi.nlm.nih.gov/16398734